水貂作为新型实验动物模型的应用研究  

Application of mink as a new experimental animal model

作　　者：何佳蕾 何松[1] 张晴[1] 张曦文[1] 张贺 袁宝[1] 陈健[1] 任文陟[1] 胡进平[1] 丁瑜[1] HE Jialei;HE Song;ZHANG Qing;ZHANG Xiwen;ZHANG He;YUAN Bao;CHEN Jian;REN Wenzhi;HU Jinping;DING Yu(College of Animal Science,Jilin University,Changchun 130062,China;Harbin Veterinary Research Institute,Chinese Academy of Agricultural Sciences,Harbin 150069,China)

机构地区：[1]吉林大学动物科学学院,长春130062 [2]中国农业科学院哈尔滨兽医研究所,哈尔滨150069

出　　处：《中国实验动物学报》2024年第11期1456-1462,共7页Acta Laboratorium Animalis Scientia Sinica

基　　金：国家重点研发计划(2023YFF0724604);吉林省科技发展计划项目(20230505037ZP)。

摘　　要：水貂(mink)作为一种小型珍贵的毛皮动物,不仅在经济上具有显著价值,还因其独特的生物学特征和与人类在呼吸系统、免疫反应等方面的相似性,逐渐展现出作为新型实验动物模型的巨大潜力。本文综述了水貂作为实验动物模型的应用研究,包括流感病毒动物感染、新型冠状病毒肺炎动物、动物行为、犬瘟热动物、呕吐、酶消化、睾丸退化及自伤行为模型中的应用。同时,本文强调了水貂动物福利的重要性,并提出了未来水貂作为实验动物模型在科学研究中的广阔前景,为后续水貂作为新型实验动物模型的广泛应用提供参考。Mink are small,fur-bearing mammals with significant economic value.They have also recently demonstrated immense potential as novel experimental animal models owing to their unique biological characteristics and similarities with humans in terms of their respiratory systems,immune responses,and other characteristics.This article comprehensively reviews applied research on the use of mink as an experimental animal model,encompassing their use as animal models for influenza virus infection,COVID-19,animal behavior,canine distemper,vomiting,enzyme digestion,testicular degeneration,and self-injurious behavior.The importance of animal welfare is also emphasized,and the broad prospects for the use of mink as an experimental animal model in scientific research are proposed,offering valuable insights and a reference for the extensive application of mink as a novel experimental animal model in the future.

关 键 词：水貂 实验动物模型 应用研究 

分 类 号：Q95-33[生物学—动物学]