基于因子分析和聚类分析的194例结直肠息肉患者中医证候分型及特点分析  

Analysis of TCM syndrome types and characteristics of 194 patients with colorectal polyps based on factor analysis and cluster analysis

作　　者：张双 刘源[1] 姬会会 杜时雨[2] ZHANG Shuang;LIU Yuan;JI Huihui;DU Shiyu(China-Japan Friendship Clinical Medical College,Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]北京中医药大学中日友好医院临床医学院,100029 [2]中日友好医院消化科

出　　处：《环球中医药》2024年第12期2510-2517,共8页Global Traditional Chinese Medicine

基　　金：北京市自然科学基金(7202181)。

摘　　要：目的运用因子分析联合聚类分析探讨结直肠息肉的中医证型分布。方法采集194例结直肠息肉患者的中医四诊信息,将主要的条目纳入因子分析矩阵提取公因子,再以公因子为变量进行系统聚类分析,根据因子得分系数矩阵中得分最高的因子确定所属证型。结果因子分析共筛选出15个公因子,累计贡献率69.335%;经聚类分析分为9类,归纳为5种中医证型,其中第1类包含公因子F4、F11归纳为肠道湿热证(湿重),第2类包含公因子F6、F14归纳为肝郁脾虚证,第3类包含公因子F12、F13归纳为脾虚湿困证,第4类包含公因子F5、F15归纳为中脏虚寒证,第5类和第9类包含公因子F3、F7归纳为肾阳不足证,第6类包含公因子F8、F9归纳为肝郁气滞证,第7类包含公因子F1、F10归纳为肠道湿热证(兼血瘀),第8类包含公因子F2归纳为肠道湿热证(热重)。根据因子得分系数矩阵中得分最高的因子确定所属证型,194例中肠道湿热证(69例,35.57%)、肝郁脾虚证(51例,26.29%)、肾阳不足证(26例,13.40%)、中虚脏寒证(25例,12.89%)、脾虚湿困证(23例,11.86%)。结论结直肠息肉患者的中医证型为肠道湿热证、肝郁脾虚证、肾阳不足证、中虚脏寒证、脾虚湿困证,其中肠道湿热证最常见,不同证型患者间年龄、病理类型存在差异。Objective Explore the distribution of traditional Chinese medicine(TCM)syndrome types of colorectal polyps by factor analysis and cluster analysis.Methods The TCM four diagnostic information of 194 patients with colorectal polyps were collected,and the main items were included in the factor analysis matrix to extract the common factors,and then the common factors were used as variables for systematic cluster analysis.the syndrome type was determined according to the factor with the highest score in the factor score coefficient matrix.Results A total of 15 common factors were selected by factor analysis,and the cumulative contribution rate was 69.335%.The first category included common factors F4 and F11 as intestinal damp-heat syndrome(damp weight),the second included common factors F6 and F14 as liver stagnation and spleen deficiency syndrome,the third included common factors F12 and F13 as spleen deficiency and dampness syndrome,the fourth included common factors F5 and F15 as middle visceral deficiency-cold syndrome,and category 5 and 9 includes common factors F3 and F7 as kidney-yang deficiency syndrome.The sixth category included common factors F8 and F9 as liver depression and qi stagnation syndrome,the seventh included common factors F1 and F10 as intestinal damp-heat syndrome(and blood stasis),and the eighth includes common factor F2 as intestinal damp-heat syndrome(heat weight).The syndrome type was determined according to the factor with the highest score in the factor score coefficient matrix,including intestinal damp-heat syndrome(69 cases,35.57%),liver depression and spleen deficiency syndrome(51 cases,26.29%),kidney yang deficiency syndrome(26 cases,13.40%),middle deficiency and visceral cold syndrome(25 cases,12.89%),spleen deficiency and dampness syndrome(23 cases,11.86%).Conclusion The TCM syndrome types of patients with colorectal polyps are intestinal damp-heat syndrome,liver depression and spleen deficiency syndrome,kidney yang deficiency syndrome,middle deficiency and visceral cold syndrome a

关 键 词：结直肠息肉 中医四诊信息 证候分型 聚类分析 因子分析 数据挖掘 

分 类 号：R269[医药卫生—中西医结合]