中国中老年良性前列腺增生/下尿路症状人群合并抑郁症的危险因素分析  

Risk factors for depression in middle-aged and elderly males with benign prostatic hyperplasia/lower urinary tract symptoms

作　　者：盛正成 沈天一 唐朝朋 周昱霖 许松 周文泉 SHENG Zheng-cheng;SHEN Tian-yi;TANG Chao-peng;ZHOU Yu-lin;XU Song;ZHOU Wen-quan(Department of Urology,General Hospital of Eastern Theater Command,Nanjing,Jiangsu 210002,China)

机构地区：[1]东部战区总医院泌尿外科,江苏南京210002

出　　处：《中华男科学杂志》2024年第12期1105-1109,共5页National Journal of Andrology

基　　金：东部战区总医院院内课题(2023JCYJYB114)。

摘　　要：目的:探讨中国中老年男性良性前列腺增生/下尿路症状(BPH/LUTS)患者合并抑郁症的危险因素。方法:基于2018年中国健康与养老追踪调查(CHARLS)数据,纳入≥45岁的中老年男性参与者8426例,利用logistic回归分析探讨BPH/LUTS患者合并抑郁症的危险因素。结果:中老年BPH/LUTS患者共1447例,患病率为17.2%。合并抑郁症的患者529例,患病率36.5%。Logistic回归分析结果显示:合并基础疾病(OR=1.29,95%CI 1.03~1.62)是BPH/LUTS患者并发抑郁症的危险因素。高中及以上受教育水平(OR=0.52,95%CI 0.36~0.75)、居住在城市(OR=0.75,95%CI 0.60~0.95)、东部地区(OR=0.61,95%CI 0.38~0.97)、睡眠6~9 h(OR=0.52,95%CI 0.41~0.66)是BPH/LUTS患者并发抑郁症的保护因素。结论:合并基础疾病、受教育水平、居住区域、地区、睡眠时长对中国中老年男性BPH/LUTS患者合并抑郁症产生影响,值得临床关注。Objective:To investigate the risk factors for depression in middle-aged and elderly Chinese male patients with benign prostatic hyperplasia/lower urinary tract symptoms(BPH/LUTS).Methods:Based on the data from the 2018 China Health and Retirement Longitudinal Study(CHARLS),we included 8426 male participants aged≥45 years in this study,and explored the risk factors for depression in patients with BPH/LUTS by logistic regression analysis.Results:Among the total number of participants,there were 1447 cases of BPH/LUTS,with a prevalence rate of 17.2%,and 36.5%of the patients(529/1447)were complicated by depression.Logistic regression analysis showed that underlying diseases were the risk factors for depression in patients with BPH/LUTS(OR=1.29,95%CI:1.03-1.62),while the protective factors against the condition included high school education or above(OR=0.52,95%CI:0.36-0.75),urban residence(OR=0.75,95%CI:0.60-0.95),eastern region(OR=0.61,95%CI:0.38-0.97),and 6-9 h/d sleep(OR=0.52,95%CI:0.41-0.66).Conclusion:Underlying diseases,education level,residential area,geographical region,and sleep duration are influencing factors for depression in middle-aged and elderly male patients with BPH/LUTS in China and deserve the attention of clinicians.

关 键 词：良性前列腺增生/下尿路症状 中国健康与养老追踪调查 抑郁症 LOGISTIC分析 

分 类 号：R697.32[医药卫生—泌尿科学]