经皮穴位仿生物电刺激调控炎症因子表达对人流术后子宫内膜修复的作用研究  

Study on the Effect of Transcutaneous Acupoint Bioelectric Stimulation Regulating the Expression of Inflammatory Factors on Endometrial Repair after Artificial Abortion

作　　者：汤洁 邹丽莎 张伶俐[1] 谭艳姣 黄群[1] TANG Jie;ZOU Li-sha;ZHANG Ling-li;TAN Yan-jiao;HUANG Qun(Department of Gynecology,The First Affiliated Hospital of Hunan Traditional Chinese Medicine College(Hunan Provincial Traditional Chinese Medicine Hospital),Zhuzhou,Hunan,412000,China)

机构地区：[1]湖南中医药高等专科学校附属第一医院(湖南省直中医医院)妇科,湖南株洲412000

出　　处：《现代生物医学进展》2024年第23期4552-4554,4558,共4页Progress in Modern Biomedicine

基　　金：湖南省卫生健康委科研计划项目(202305017843)。

摘　　要：目的:探讨经皮穴位仿生物电刺激调控炎症因子表达对人流术后子宫内膜修复的作用研究。方法:120例行人工流产术患者分为空白组(n=40,术后给予常规抗感染治疗)、对照组(n=40,空白组基础上采用仿生物电刺激治疗)和观察组(n=40,空白组基础上采用经皮穴位仿生物电刺激治疗)。对比三组子宫内膜厚度、阴道流血量、炎症因子[肿瘤坏死因子-α(TNF-α)、白细胞介素(IL)-8、IL-4、IL-10]、月经复潮时间、再次清宫发生率及盆腔炎性疾病发病率。结果:治疗后,观察组阴道流血量、TNF-α、IL-8水平均低于对照组和空白组,子宫内膜厚度大于空白组、对照组,IL-4、IL-10水平均高于对照组和空白组(P<0.05)。治疗后,观察组再次清宫发生率、盆腔炎性疾病发病率均低于空白组、对照组,月经复潮时间短于空白组、对照组(P<0.05)。结论:人流术后患者接受经皮穴位仿生物电刺激后,可通过调控炎症因子表达促进子宫内膜修复并改善临床症状。Objective:To investigate the effect of transcutaneous acupoint bioelectric stimulation on regulating the expression of inflammatory factors on endometrial repair after artificial abortion.Methods:120 patients who underwent artificial abortion were divided into blank group(n=40,routine anti-infection treatment after operation),control group(n=40,bioelectric stimulation treatment on the basis of blank group)and observation group(n=40,transcutaneous acupoint bioelectric stimulation treatment on the basis of blank group).The endometrial thickness,vaginal bleeding volume,inflammatory factors[tumor necrosis factor-α(TNF-α),interleukin(IL)-8,IL-4,IL-10],menstrual recovery time,incidence of uterine curettage again and incidence of pelvic inflammatory disease were compared among three groups.Results:After treatment,the vaginal bleeding volume,TNF-αand IL-8 in observation group were lower than those in control group and blank group,and the endometrial thickness was greater than that in blank group and control group(P<0.05).And the levels of IL-4 and IL-10 were higher than those in control group and blank group(P<0.05).After treatment,the incidence of uterine curettage again and the incidence of pelvic inflammatory disease in observation group were lower than those in blank group and control group,and the time of menstruation recovery was shorter than that in blank group and control group(P<0.05).Conclusion:Patients after artificial abortion receiving transcutaneous acupoint bioelectric stimulation,which can promote endometrial repair and improve clinical symptoms by regulating the expression of inflammatory factors.

关 键 词：经皮穴位仿生物电刺激 子宫内膜 炎症因子 人工流产术 

分 类 号：R711[医药卫生—妇产科学]