静脉内热消融术联合泡沫硬化剂治疗下肢静脉曲张的临床疗效观察  

Clinical observation on the therapeutic effect of intravenous thermal ablation combined with foam sclerosing agent in the treatment of varicose veins of lower limbs

作　　者：黄淼文 HUANG Miaowen(General Surgery Department of Gastroenterology,The Second Affiliated Hospital of Xiamen Medical College,Xiamen,Fujian,361021,China)

机构地区：[1]厦门医学院附属第二医院普外胃肠外科,福建厦门361021

出　　处：《中国冶金工业医学杂志》2024年第6期624-625,共2页Chinese Medical Journal of Metallurgical industry

摘　　要：目的探究静脉内热消融术(EVTA)联合泡沫硬化剂治疗下肢静脉曲张的临床疗效。方法选取我院2020年1月—2022年11月收治的64例下肢静脉曲张患者,采用随机数字表法分为观察组与对照组,每组各32例。对照组采用大隐静脉高位结扎加抽剥术治疗,观察组采用980 nm激光静脉内热消融术联合泡沫硬化剂治疗。比较两组治疗前后的静脉疾病临床严重程度评分表(VCSS)评分、Aberdeen静脉曲张调查问卷(AVVQ)评分、血小板计数(PLT)、血小板平均体积(MPV)以及手术情况和不良反应发生情况。结果观察组治疗后的VCSS、AVVQ评分和PLT、MPV水平以及手术时间、下床活动时间和术中出血量均优于对照组,组间比较差异显著(t=12.114、11.885、4.612、15.015、15.007、6.518、13.638,均P<0.05);观察组的不良反应发生率略低于对照组,但组间比较无显著差异(χ^(2)=0.784,P>0.05)。结论EVTA联合泡沫硬化剂可改善下肢静脉曲张患者的临床症状和血小板水平,减少术中出血量和手术时间,治疗安全性高。Objective To investigate the clinical efficacy of endovenous thermal ablation(EVTA)combined with foam sclerotherapy in the treatment of lower limb varicose veins.Methods A total of 64 patients with lower limb varicose veins treated in our hospital from January 2020 to November 2022 were selected and randomly divided into an observation group and a control group,with 32 cases in each group.The control group was treated with high ligation and stripping of the great saphenous vein,while the observation group received 980 nm laser EVTA combined with foam sclerotherapy.The venous clinical severity score(VCSS),Aberdeen Varicose Vein Questionnaire(AVVQ)score,platelet count(PLT),mean platelet volume(MPV),as well as surgical outcomes and incidence of adverse reactions,were compared between the two groups before and after treatment.Results The VCSS,AVVQ scores,and levels of PLT and MPV in the observation group after treatment,along with surgical time,time to ambulation,and intraoperative blood loss,were all significantly better than those in the control group(t=12.114,11.885,4.612,15.015,15.007,6.518,13.638,all P<0.05).The incidence of adverse reactions in the observation group was slightly lower than in the control group,but the difference was not statistically significant(χ^(2)=0.784,P>0.05).Conclusion EVTA combined with foam sclerotherapy can improve clinical symptoms and platelet levels in patients with lower limb varicose veins,reduce intraoperative blood loss and surgery time,and is associated with high treatment safety.

关 键 词：静脉内热消融术 泡沫硬化剂 下肢静脉曲张 临床疗效 

分 类 号：R543.6[医药卫生—心血管疾病]