高雄激素血症影响多囊卵巢综合征肝脏功能的研究进展  

Research progress of hyperandrogenism affecting liver function in polycystic ovary syndrome

作　　者：南忱 齐红敏 王东旭[2] Nan Chen;Qi Hongmin;Wang Dongxu(Gastrointestinal Endoscopy Center,People's Hospital of China Medical University&Liaoning Provincial People's Hospital,Shenyang 110067,China;Department of Gastroenterology,Shengjing Hospital of China Medical University,Shenyang 110004,China)

机构地区：[1]中国医科大学人民医院,辽宁省人民医院消化内镜中心,沈阳110067 [2]中国医科大学附属盛京医院消化内科,沈阳110004

出　　处：《中国综合临床》2024年第6期477-480,共4页Clinical Medicine of China

基　　金：辽宁省科学技术计划联合基金博士科研启动项目(2023-BSBA-349)。

摘　　要：多囊卵巢综合征(polycystic ovary syndrome, PCOS)是育龄期女性常见的疾病, 高雄激素血症(hyperandrogenism, HA)是PCOS患者典型的临床特征。近年来的研究发现, HA除引起PCOS患者的生殖、内分泌及代谢紊乱外, 也与PCOS患者的肝脏功能密切相关。现从PCOS与HA、HA对PCOS患者肝脏功能的影响、HA影响PCOS肝脏功能的机制以及干预HA对PCOS肝脏功能的改善四个方面进行综述, 旨在进一步提高HA对PCOS患者多系统影响的重视, 为改善PCOS患者的肝脏功能和临床预后提供依据与思路。Polycystic ovary syndrome(PCOS)is a common disease among women of childbearing age,and hyperandrogenism(HA)is a typical clinical feature of PCOS patients.In recent years,research has found that HA is closely related to the liver function of PCOS patients,in addition to causing reproductive,endocrine,and metabolic disorders.This article provides a review from four aspects:the relationship between PCOS and HA,the impact of HA on liver function in PCOS patients,the mechanism of HA affecting liver function in PCOS,and the intervention of HA on improving liver function in PCOS.The aim is to further raise awareness of the multi system effects of HA on PCOS patients and provide a basis and approach for improving liver function and clinical prognosis in PCOS patients.

关 键 词：高雄激素血症 多囊卵巢综合征 肝脏功能 

分 类 号：R711.75[医药卫生—妇产科学]