中药热敷联合体外冲击波治疗膝骨关节炎寒湿痹阻证临床研究  

Clinical Study on Chinese Medicine Hot Compress Combined with Extracorporeal Shock Wave for Knee Osteoarthritis with Cold-Damp Bi Obstruction Syndrome

作　　者：王强力 徐欢欢[1] 郑贺彬 陈宁宁[1] WANG Qiangli;XU Huanhuan;ZHENG Hebin;CHEN Ningning(Wenzhou TCM Hospital of Zhejiang Chinese Medical University,Wenzhou Zhejiang 325000,China)

机构地区：[1]浙江中医药大学附属温州市中医院,浙江温州325000

出　　处：《新中医》2024年第24期79-83,共5页New Chinese Medicine

摘　　要：目的:观察中药热敷联合体外冲击波治疗膝骨关节炎寒湿痹阻证的临床疗效。方法:选取132例膝骨关节炎寒湿痹阻证患者,以随机数字表法分为对照组、试验组,每组66例。对照组予体外冲击波治疗,试验组予中药热敷联合体外冲击波治疗,2组均治疗4周。比较2组临床疗效、西安大略和麦克马斯特大学骨关节炎调查量表(WOMAC)评分、Lysholm膝关节功能评分量表(LKS)评分及血清缓激肽(BK)、前列腺素E2(PGE2)、5-羟色胺(5-HT)水平。结果:治疗后,总有效率试验组92.06%,高于对照组77.78%(P<0.05)。2组WOMAC评分均较治疗前降低(P<0.05),LKS评分均较治疗前升高(P<0.05);试验组WOMAC评分低于对照组(P<0.05),LKS评分高于对照组(P<0.05)。2组血清BK、PGE2、5-HT水平均较治疗前降低(P<0.05),试验组血清BK、PGE2、5-HT水平均低于对照组(P<0.05)。结论:中药热敷联合体外冲击波治疗膝骨关节炎寒湿痹阻证疗效优于单独使用体外冲击波治疗,可改善病情,进一步降低疼痛介质水平。Objective:To observe the clinical effect of Chinese medicine hot compress combined with extracorporeal shock wave on knee osteoarthritis with cold-damp bi obstruction syndrome.Methods:A total of 132 cases of patients with knee osteoarthritis with cold-damp bi obstruction syndrome were selected and divided into the control group and the trial group using a random number table method,with 66 cases in each group.The control group received extracorporeal shock wave therapy,and the trial group received Chinese medicine hot compress combined with extracorporeal shock wave therapy.Both groups were treated for four weeks.Compared the clinical efficacy,Western Ontario and McMaster Universities Arthritis Index(WOMAC)scores,Lysholm Knee Score(LKS),and levels of bradykinin(BK),prostaglandin E2(PGE2)and 5-hydroxytryptamine(5-HT)in serum between the two groups.Results:After treatment,the total effective rate was 92.06%in the trial group,which was higher than that of 77.78%in the control group(P<0.05).The WOMAC scores in both groups were decreased when compared with those before treatment(P<0.05),and the LKS scores were increased when compared with those before treatment(P<0.05);the WOMAC score in the trial group was lower than that in the control group(P<0.05),and the LKS score was higher than that in the control group(P<0.05).The levels of serum BK,PGE2,and 5-HT in both groups were decreased when compared with those before treatment(P<0.05),and the levels of serum BK,PGE2,and 5-HT in the trial group were lower than those in the control group(P<0.05).Conclusion:The combination of Chinese medicine hot compress and extracorporeal shock wave therapy is more effective in treating knee osteoarthritis with cold-damp bi obstruction syndrome than using extracorporeal shock wave therapy alone,which can improve the condition of disease and further reduce the level of pain mediators.

关 键 词：膝骨关节炎 寒湿痹阻证 中药热敷 体外冲击波 膝关节功能 疼痛介质 

分 类 号：R684.3[医药卫生—骨科学]