利多卡因联合盐酸肾上腺素注射液表面麻醉在翼状胬肉切除术中的应用效果  

The Effect of Surface Anaesthesia with Lidocaine Combined with Epinephrine Hydrochloride in Pterygium Excision

作　　者：李丽萍 谭婷 吴艳 江慧敏 李财保 LI Liping;TAN Ting;WU Yan;JIANG Huimin;LI Caibao(The Second People's Hospital of Jingdezhen,Jingdezhen Jiangxi 333000,China)

机构地区：[1]景德镇市第二人民医院,江西景德镇333000

出　　处：《药品评价》2024年第8期975-978,共4页Drug Evaluation

基　　金：景德镇市科技局科技计划项目(20231SFZC070)。

摘　　要：目的评估利多卡因联合盐酸肾上腺素注射液作为表面麻醉剂在翼状胬肉切除术中的应用效果。方法选取2023年1月至2024年4月期间在景德镇市第二人民医院眼科行翼状胬肉切除术患者112例(112眼)为研究对象,依据不同的麻醉方式将患者随机分为试验组与对照组,每组各56例(56眼)。试验组给予利多卡因注射液+盐酸肾上腺素注射液表面麻醉,对照组给予利多卡因注射液局部浸润麻醉。比较两组手术效果、手术时间、视觉模拟评分系统(VAS)评分、结膜充血情况、术野清晰度、术中止血发生情况。结果试验组治愈率为98.21%,对照组治愈率为92.86%,差异无统计学意义(P>0.05)。试验组的手术时间短于对照组,差异有统计学意义(P<0.05);但两组术中10 min及术后VAS评分比较,差异无统计学意义(P>0.05)。试验组术中结膜充血评分优于对照组,差异有统计学意义(P<0.01)。试验组术野清晰度高于对照组,需要止血者所占比例低于对照组,差异有统计学意义(P<0.05)。结论利多卡因联合盐酸肾上腺素作为翼状胬肉切除术中的表面麻醉剂,可以有效提高麻醉效果和术野清晰度,减少结膜充血和术中出血,从而缩短手术时间,促进术后恢复。Objective To evaluate the effect of lidocaine combined with epinephrine hydrochloride as a surface anaesthetic in pterygium excision.Methods 112 patients(112 eyes)who underwent pterygium excision in the Department of Ophthalmology of The Second People's Hospital of Jingdezhen during the period of January 2023 to April 2024 were selected for the study,and the patients were randomly divided into the experimental group and the control group according to the different methods of anaesthesia,with 56 patients(56 eyes)in each group.The experimental group was given lidocaine injection and epinephrine hydrochloride injection for surface anaesthesia,and the control group was given lidocaine injection for local infiltration anaesthesia.The patients in the two groups were compare the surgical outcome,operative time,visual analogue scoring system(VAS)score,conjunctival congestion,clarity of the operative field,and the occurrence of intraoperative haemostasis.Results The cure rate of the experimental group was 98.21%,and the cure rate of the control group was 92.86%,the difference was not statistically significant(P>0.05).The operation time of the experimental group was shorter than that of the control group,the difference was statistically significant(P<0.05);but the difference between the two groups was not statistically significant when comparing the intraoperative 10 min and postoperative VAS scores(P>0.05).The intraoperative conjunctival congestion score of the experimental group was better than that of the control group,the difference was statistically significant(P<0.01).The operative field clarity of the experimental group was higher than that of the control group,and the percentage of those who needed haemostasis was lower than that of the control group,and the difference between the two groups was statistically significant(P<0.05).Conclusion Lidocaine combined with epinephrine hydrochloride as a surface anaesthetic in pterygium excision can effectively improve anaesthesia effect and clarity of the operative field,red

关 键 词：利多卡因 盐酸肾上腺素 翼状胬肉 表面麻醉 手术治疗 

分 类 号：R614[医药卫生—麻醉学]