糖尿病合并结核分枝杆菌潜伏感染的流行特征与筛查干预  

Prevalence characteristics and screening interventions of diabetes combined with latent mycobacterium tuberculosis infection

作　　者：张璇(综述) 付海艳 杜映荣(审校) ZHANG Xuan;FU Haiyan;DU Yingrong(Department of Care,Third People's Hospital of Kunming/Yunnan Provincial Clinical Medical Center,Kunming Yunnan 650041,China;Department of Infection,Third People's Hospital of Kunming/Yunnan Provincial Clinical Medical Center,Kunming Yunnan 650041,China)

机构地区：[1]昆明市第三人民医院/云南省传染性疾病临床医学中心关怀科,云南昆明650041 [2]昆明市第三人民医院/云南省传染性疾病临床医学中心感染科,云南昆明650041

出　　处：《云南医药》2024年第6期87-91,共5页Medicine and Pharmacy of Yunnan

基　　金：云南省科技厅重大专项(202402AA310011)。

摘　　要：LTBI有5%~15%的风险进展为活动性结核,是结核病病情难以控制的原因之一。糖尿病患者是MTB的易感人群,也是LTBI的危险因素。目前,我国两病共患水平相比全球较高,且共患率呈上升趋势,但仍尚缺乏针对糖尿病患者LTBI的大规模筛查以及相关干预措施。由此,两病共患为我国结核病疫情防控带来了巨大挑战。故本文将针对糖尿病与LTBI共病的国内外流行状况、危险因素以及患者的早期筛查与干预方式进行综述,以期对结核病的预防与控制提供参考意见。LTBI has a 5%to 15%risk of progressing to active TB and is one of the reasons why TB disease is difficult to control.Diabetic patients are susceptible to MTB and are also risk factors for LTBI.Currently,the level of co-morbidity in China is higher than that in the world,and the co-morbidity rate is on the rise,but there is still a lack of large-scale screening and related intervention measures for LTBI in diabetic patients.As a result,the co-occurrence of the two diseases has brought great challenges for the prevention and control of the TB epidemic in China.Therefore,this paper will review the prevalence,risk factors and early screening and intervention methods of diabetes mellitus and LTBI,in order to provide reference for the prevention and control of TB.

关 键 词：糖尿病 结核潜伏性感染 流行现状 危险因素 

分 类 号：R587.2[医药卫生—内分泌] R52[医药卫生—内科学]