变应性鼻炎及鼻咽比率与儿童腺样体肥大声导抗分析的相关性研究  

Correlation study of allergic rhinitis and A/N ratio in acoustic immitance analysis of adenoid hypertrophy in children

作　　者：杨亮 王川 石丽芳[1,2] 王国庆 陆飞彩 Yang Liang;Wang Chuan;Shi Lifang;Wang Guoqing;Lu Feicai(Department of Otorhinolaryngology Head and Neck Surgery,Suqian First Hospital,Suqian 223800,China;Department of Otorhinolaryngology Head and Neck Surgery,the Affiliated Suqian First Peoples Hospital of Nanjing Medical University,Suqian 223800,China)

机构地区：[1]宿迁市第一人民医院耳鼻咽喉头颈外科,宿迁223800 [2]南京医科大学附属宿迁第一人民医院耳鼻咽喉头颈外科,宿迁223800

出　　处：《国际耳鼻咽喉头颈外科杂志》2024年第6期311-314,共4页International Journal of Otolaryngology-Head and Neck Surgery

基　　金：江苏省科研与实践创新计划(XJCX20_0930)。

摘　　要：目的探讨儿童腺样体肥大的不同鼓室导抗图与鼻咽比率(A/N比值)及变应性鼻炎的相关性及其影响因素。方法回顾性分析2022年1月至6月因腺样体肥大就诊于宿迁市第一人民医院耳鼻咽喉头颈外科并手术治疗的140例患儿临床资料,通过建立受试者工作特征(ROC)曲线,确定腺样体肥大患儿A/N比值的最佳截点,并通过卡方检验、单因素和多因素分析评估年龄、性别、A/N比值、体重指数(BMI)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)水平及是否存在变应性鼻炎与腺样体肥大患儿声导抗的关系。结果根据ROC曲线计算出A/N的临界值为0.84。A/N比值、HDL水平及存在变应性鼻炎与腺样体肥大患儿声导抗之间差异有统计学意义(P<0.05),而年龄、性别、BMI及LDL水平与腺样体肥大患儿声导抗之间差异无统计学意义(P>0.05)。多因素分析结果显示A/N比值及存在变应性鼻炎与腺样体肥大患儿声导抗之间的差异有统计学意义(P<0.05)。结论A/N比值及是否存在变应性鼻炎是判断腺样体肥大伴发分泌性中耳炎的重要依据。Objective To investigate the correlation of tympanic immittance map with A/N ratio and allergic rhinitis in children with adenoid hypertrophy and its impact factors.Methods The clinical data of 140 children with adenoid hypertrophy treated in Department of Otorhinolaryngology Head and Neck Surgery,Suqian First People's Hospital from January to June 2022 were retrospectively analyzed.The optimal cut-off point of adenoid-nasopharyngeal ratio(A/N ratio)was determined by establishing receiver operating characteristic curve(ROC curve).The relationship between age,sex,A/N ratio,BMI,LDL,HDL levels and the presence of allergic rhinitis and adenoid hypertrophy was evaluated by Chi-square test,Univariate and Multivariate analysis.Results The critical value of A/N was calculated as O.84 according to ROC curve.The A/N ratio,HDL level and allergic rhinitis were significantly correlated with acoustic transduction in children with adenoid hypertrophy(P<0.05).There were no significant correlation between age,sex,BMI and LDL level and acoustic transduction in children with adenoid hypertrophy(P>0.05).The results of multivariate analysis showed that the A/N ratio and the presence of allergic rhinitis were significantly correlated with acoustic transduction in children with adenoid hypertrophy(P<0.05).Conclusions The A/N ratio and allergic rhinitis are the important basis for the diagnosis of adenoid hypertrophy with secretory otitis media.

关 键 词：鼻炎 变应性 季节性 儿童 腺样体肥大 A/N比值 声导抗 

分 类 号：R765.21[医药卫生—耳鼻咽喉科] R766[医药卫生—临床医学]