超声造影在早中期非创伤性股骨头坏死中的诊断价值  

Diagnostic Value of Contrast-enhanced Ultrasound in Early and Middle Stage Nontraumatie Osteoneerosis of Femoral Head

作　　者：顾霞 黄勇 GU Xia;HUANG Yong(Department of General Practice,Hai’an Traditional Chinese Medicine Hospital,Hai’an 226600,China;不详)

机构地区：[1]海安市中医院全科,江苏海安226600 [2]海安市中医院超声科,江苏海安226600

出　　处：《中国医学创新》2024年第36期120-123,共4页Medical Innovation of China

摘　　要：目的:探讨超声造影(CEUS)在早中期非创伤性股骨头坏死(NONFH)诊断中的价值。方法:将2021年10月—2023年10月在海安市中医院确诊的105例NONFH患者作为研究组,并依据国际骨循环学会(ARCO)分期将其分为早期组(n=40)和中期组(n=65),同期纳入健康个体40例作为对照组。所有患者均接受CEUS检查,进行CEUS定量参数[达峰时间(TTP)、增强强度(EI)、平均渡越时间(MTT)、上升斜率(AS)和下降斜率(DS)]分析。通过受试者操作特征(ROC)曲线分析CEUS参数在早中期NONFH诊断中的效能。结果:中期组、早期组的EI、AS均大于对照组,TTP、MTT均早于对照组,DS均小于对照组(P<0.05);中期组的EI、AS均大于早期组(P<0.05);CEUS参数联合诊断早中期NONFH的敏感度和特异度分别为93.3%、100%,AUC为0.986。结论:CEUS在早中期NONFH的诊断中具有重要价值,尤其是量化参数联合应用时表现出优秀的敏感度和特异度。Objective:To explore the value of contrast-enhanced ultrasound(CEUS)in the diagnosis of early and middle stage nontraumatie osteoneerosis of femoral head(NONFH).Method:A total of 105 patients with NONFH diagnosed in Hai’an Traditional Chinese Medicine Hospital from October 2021 to October 2023 were selected as the study group,and they were divided into early group(n=40)and middle group(n=65)according to the association research circulation osseous(ARCO)stage,and 40 healthy individuals in the same period were included as the control group.All patients underwent CEUS examination,and CEUS quantitative parameters[time to peak(TTP),enhancement intensity(EI),mean transit time(MTT),ascending slope(AS)and descending slope(DS)]were analyzed.The efficacy of CEUS parameters in early and middle stage NONFH diagnosis were analyzed by receiver operating characteristic(ROC)curve.Result:EI and AS in middle group and early group were higher than those in control group,TTP and MTT were earlier than those in control group,and DS was lower than that in control group (P<0.05). EI and AS in middle group were higher than those in early group (P<0.05). The sensitivity and specificity of CEUS parameters combined in the diagnosis of early and middle stage NONFH were 93.3% and 100%, respectively, and the AUC was 0.986. Conclusion: CEUS has important value in the diagnosis of early and middle stage NONFH, especially when combined with quantitative parameters, showing excellent sensitivity and specificity.

关 键 词：超声造影 非创伤性股骨头坏死 国际骨循环学会分期 微循环 

分 类 号：R681.8[医药卫生—骨科学] R445.1[医药卫生—外科学]