支气管肺泡灌洗术联合头孢曲松在儿童大叶性肺炎中的应用效果  

Application effect of bronchoalveolar lavage combined with ceftriaxone in children with lobar pneumonia

作　　者：赵启锋 李万海 ZHAO Qifeng;LI Wanhai(Ankang Maternal and Child Health Hospital,Ankang 725000;the People's Hospital of Ziyang County,Ankang 725300,China)

机构地区：[1]陕西省安康市妇幼保健院,陕西安康725000 [2]陕西省安康市紫阳县人民医院,陕西安康725300

出　　处：《临床医学研究与实践》2024年第35期94-97,共4页Clinical Research and Practice

摘　　要：目的探讨支气管肺泡灌洗术联合头孢曲松在儿童大叶性肺炎中的应用效果。方法选取2022年5月至2023年4月收治的90例大叶性肺炎患儿为研究对象,按照治疗方式的不同将其分为对照组(45例,对症治疗+头孢曲松)和观察组(45例,在对照组基础上加用支气管肺泡灌洗术)。比较两组的治疗效果。结果观察组的治疗总有效率为100.00%,显著高于对照组的86.67%(P<0.05)。治疗后,观察组的用力肺活量(FVC)、呼气流量峰值(PEF)及第1秒用力呼气容积(FEV_(1))显著高于对照组(P<0.05)。治疗后,观察组的动脉血二氧化碳分压(PaCO_(2))低于对照组,动脉血氧分压(PaO_(2))、动脉血氧饱和度(SaO_(2))高于对照组(P<0.05)。治疗后,观察组的降钙素原(PCT)、C反应蛋白(CRP)水平明显低于对照组(P<0.05)。观察组的退热时间、咳嗽缓解时间、肺啰音消失时间及住院时间短于对照组,差异具有统计学意义(P<0.05)。结论支气管肺泡灌洗术联合头孢曲松治疗儿童大叶性肺炎的临床效果显著,可提高肺功能,改善血气指标及炎症指标,促进患儿恢复。Objective To explore the application effect of bronchoalveolar lavage combined with ceftriaxone in children with lobar pneumonia.Methods A total of 90 children with lobar pneumonia admitted from May 2022 to April 2023 were selected as the research objects.According to the different treatment methods,the children were divided into control group(45 cases,symptomatic treatment+ceftriaxone)and observation group(45 cases,bronchoalveolar lavage was added on the basis of the control group).The therapeutic effects of the two groups were compared.Results The total effective rate of treatment in the observation group was 100.00%,which was significantly higher than 86.67%in the control group(P<0.05).After treatment,the forced vital capacity(FVC),peak expiratory flow(PEF)and forced expiratory volume in one second(FEV_(1))in the observation group were significantly higher than those in the control group(P<0.05).After treatment,the arterial partial pressure of carbon dioxide(PaCO_(2))in the observation group was lower than that in the control group,and the arterial partial pressure of oxygen(PaO_(2))and arterial oxygen saturation(SaO_(2))were higher than those in the control group(P<0.05).After treatment,the levels of procalcitonin(PCT)and C-reactive protein(CRP)in the observation group were significantly lower than those in the control group(P<0.05).The antipyretic time,cough relief time,lung rale disappearance time and hospitalization time in the observation group were shorter than those in the control group,and the differences were statistically significant(P<0.05).Conclusion Bronchoalveolar alveolar lavage combined with ceftriaxone in the treatment of lobar pneumonia in children has a significant clinical effect,it can improve lung function,blood gas indexes and inflammation indexes,and promote the recovery of children.

关 键 词：儿童 头孢曲松 支气管肺泡灌洗术 大叶性肺炎 血气指标 炎症指标 

分 类 号：R725.6[医药卫生—儿科]