银翘散联合西药治疗小儿热性惊厥的临床效果  

Clinical effect of Yinqiao powder combined with western medicine in the treatment of febrile convulsion in children

作　　者：朱琨 张琼香 季伟 ZHU Kun;ZHANG Qiongxiang;JI Wei(Pediatrics Department,Yancheng First Hospital Affiliated of Nanjing University Medical College/Yancheng No.1 People's Hospital,Yancheng 224005,China)

机构地区：[1]南京大学医学院附属盐城第一医院/盐城市第一人民医院儿科,江苏盐城224005

出　　处：《临床医学研究与实践》2024年第35期126-129,共4页Clinical Research and Practice

摘　　要：目的探讨银翘散联合西药治疗小儿热性惊厥的有效性与安全性,以期为临床治疗提供更多的选择。方法选取2021年1月至2022年1月我科住院治疗的80例小儿热性惊厥患儿为研究对象,采用随机数字表法将其分为对照组和联合组,每组40例。对照组接受常规西药治疗,联合组在常规西药治疗基础上给予银翘散治疗。比较两组的临床疗效、发热持续时间、惊厥持续时间、呼吸道症状缓解时间、炎性因子水平及不良反应发生情况。结果联合组的治疗总有效率高于对照组(P<0.05)。联合组的发热持续时间、惊厥持续时间及呼吸道症状缓解时间均短于对照组(P<0.05)。治疗后,两组的白细胞介素-6(IL-6)、超敏C反应蛋白(hs-CRP)水平均降低,且联合组低于对照组(P<0.05)。两组的不良反应总发生率比较,差异无统计学意义(P>0.05)。结论银翘散联合西药治疗小儿热性惊厥在抑制炎症、缓解发热、缓解惊厥症状方面相较于常规西药有显著优势,且安全性较高。Objective To explore the efficacy and safety of Yinqiao powder combined with western medicine in the treatment of febrile convulsion in children,in order to provide more choices for clinical treatment.Methods A total of 80 children with febrile convulsion who were hospitalized in our department from January 2021 to January 2022 were selected as the research objects.The children were divided into control group and combined group by random number table method,with 40 cases in each group.The control group was treated with conventional western medicine,and the combined group was given Yinqiao powder treatment on the basis of conventional western medicine.The clinical efficacy,duration of fever,duration of convulsion,remission time of respiratory symptoms,levels of inflammatory factors and adverse reactions were compared between the two groups.Results The total effective rate of treatment in the combined group was higher than that in the control group(P<0.05).The duration of fever,convulsion and remission time of respiratory symptoms in the combined group were shorter than those in the control group(P<0.05).After treatment,the levels of interleukin-6(IL-6)and high sensitivity C-reactive protein(hs-CRP)in the two groups decreased,and those in the combined group were lower than the control group(P<0.05).There was no significant difference in the total incidence of adverse reactions between the two groups(P>0.05).Conclusion Yinqiao powder combined with western medicine in the treatment of febrile convulsion in children has significant advantages in inhibiting inflammation,relieving fever and convulsion symptoms compared with conventional western medicine,and has high safety.

关 键 词：小儿 热性惊厥 银翘散 

分 类 号：R725.9[医药卫生—儿科]