卵巢储备功能减退病因学的研究进展  

Research Progress on the Etiology of Diminished Ovarian Reserve

作　　者：张雯雅 吐尔逊古丽·海木都拉[2] 韩莉莉[2] 王芬[3] ZHANG Wenya;Tuerxunguli Haimudula;HAN Lili;WANG Fen(Graduate School of Xinjiang Medical University,Urumqi 830017,China;不详)

机构地区：[1]新疆医科大学研究生学院,新疆乌鲁木齐830017 [2]新疆维吾尔自治区人民医院妇科诊疗中心,新疆乌鲁木齐830001 [3]新疆维吾尔自治区人民医院生殖医学科,新疆乌鲁木齐830001

出　　处：《中国医学创新》2024年第35期174-178,共5页Medical Innovation of China

基　　金：新疆维吾尔自治区自然科学基金(2023D01C89);新疆维吾尔自治区人民医院干细胞生物治疗基础和临床研究专项项目(GXBZX-2023003)。

摘　　要：随着社会的快速发展,多孩政策的实施,以及女性个人成长与职业规划的变化,女性的结婚及生育的年龄呈现出逐渐增加的趋势。这种变化导致卵巢储备功能减退在育龄女性中的发病率逐年上升,从而引起了大众及医务人员的广泛关注。卵巢储备功能减退是指随着年龄的增加,卵母细胞的数量及质量逐渐降低,卵巢储备功能减退的女性,生育能力往往下降,自然流产发生风险较高,这是针对生殖医学领域的一大挑战。卵巢储备功能减退对女性的生育能力和生活质量产生显著影响。因此,针对这一问题,提供及时、有效的计划生育和生育治疗指导至关重要,故本文旨在对造成卵巢储备功能减退的高危因素的最新研究进展做一综述,为卵巢储备功能减退的临床治疗和预防提供一定的参考依据。With the rapid development of society,the implementation of the multi-child policy,and the changes of women's personal growth and career planning,the age of women's marriage and childbirth has shown a gradual increase.This change leads to an increase in the incidence of diminished ovarian reserve in women of childbearing age year by year,which has aroused widespread concern of the public and medical personnel.Diminished ovarian reserve function means that with the increase of age,the number and quality of oocytes gradually decrease,and the fertility of women with diminished ovarian reserve often shows a decline trend,and the risk of spontaneous abortion is higher,which is a major challenge in the field of reproductive medicine.Diminished ovarian reserve has a significant impact on a woman's fertility and quality of life.Therefore,it is very important to provide timely and effective family planning and fertility treatment guidance in response to this problem.Therefore,this paper aims to review the latest research progress on the high-risk factors causing the decline of ovarian reserve function,and provide certain reference for the clinical treatment and prevention of the decline of ovarian reserve function.

关 键 词：卵巢储备功能减退 年龄 女性不孕症 育龄期女性 

分 类 号：R711.75[医药卫生—妇产科学]