足月妊娠胎膜早破发生宫内感染危险因素分析  

Risk factors analysis of the intrauterine infection of full-term pregnant women caused by the premature rupture of fetal membranes

作　　者：王秀云[1] 唐苗苗 吴晓婕 吕红蕾 WANG Xiuyun;TANG Miaomiao;WU Xiaojie;LV Honglei(Qingdao Municipal Hospital,Qingdao,Shandong Province,266000)

机构地区：[1]青岛市市立医院,266000

出　　处：《中国计划生育学杂志》2024年第12期2886-2889,共4页Chinese Journal of Family Planning

摘　　要：目的:探讨足月胎膜早破发生宫内感染的危险因素。方法:回顾性收集2020年1月-2022年1月本院诊治的足月胎膜早破发生宫内感染患者43例临床资料为感染组,胎膜早破未发生宫内感染107例为对照组,分析足月胎膜早破发生宫内感染的危险因素。结果:单因素分析,两组年龄、体质指数、分娩史、引流产史、宫颈机能不全、孕期规律产前检查、营养不良、左室舒张末期内径、左室收缩等均未见差异(P>0.05);两组破膜至分娩时间、破膜后阴道检查次数、腹压增加、羊水过多,以及血清IL-6、PCT、CRP水平有差异(P<0.05);多因素非条件logistic分析,破膜至分娩时间>4h、破膜后阴道检查>4次、腹压增加、羊水过多,以及血清IL-6、PCT、CRP异常升高均是足月胎膜早破发生宫内感染的独立危险因素(均P<0.05);血清IL-6、PCT、CRP水平随感染程度加重而升高,与足月胎膜早破发生宫内感染患者感染程度均呈正相关(均P<0.05)。结论:足月胎膜早破发生宫内感染的独立危险因素较多,临床应针对危险因素进行干预。Objective:To study the risk factors of the intrauterine infection of full-term pregnant women caused by premature rupture of fetal membranes.Methods:The clinical data of 43 full-term women with the intrauterine infection caused by premature rupture of fetal membranes(in study group)and 1o7 full-term women without the intrauterine infection(in control group)from January 2020 to January 2022 were selected retrospectively.The risk factors of the intrauterine infection of the full-term women caused by premature rupture of fetal membranes were analyzed.Results:Univariate analysis showed that there were no significant differences in the age,the body mass index,the history of delivery,the history of induced abortion,the cervical insufficiency,the regular prenatal care during pregnancy,the malnutrition,the left ventricular end-diastolic diameter and the left ventricular contraction of the women between the two groups(P>0.05).There were significant differences in the time from the rupture of fetal membranes to the delivery,the number of vaginal examinations after rupture of membranes,the increased abdominal pressure,the polyhydramnios,and the levels of serum IL-6,PCT and CRP of the women between the two groups(P<0.05).Multivariate unconditional logistic regression analysis showed that the time from the rupture of membranes to the delivery>4h,the vaginal examination after the rupture of membranes>4 times,the increased abdominal pressure,the polyhydramnios,and the abnormal increase of serum IL-6,PCT and CRP levels of the full-term pregnant women were the independent risk factors of their intrauterine infection caused by premature rupture of fetal membranes(all P<0.05).The serum levels of IL-6,PCT and CRP of the full-term women with premature rupture of fetal membranes had increased with the severity of their intrauterine infection,and were positively correlated with the degree of their intrauterine infection(all P<0.05).Conclusion:There are many independent risk factors of the intrauterine infection of the women caused by t

关 键 词：足月妊娠 胎膜早破 宫内感染 危险因素 相关性 

分 类 号：R714.433[医药卫生—妇产科学]