某三甲中医院治疗新型冠状病毒感染病人中药处方分析  

Analysis of herbal prescriptions for treating patients with new coronavirus in a tertiary care chinese hospital

作　　者：魏良兵[1] 冉晴雨 胡兴民 高家荣[1,2] WEI Liangbing;RAN Qingyu;HU Xingmin;GAO Jiarong(Pharmacy Department,The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine,Hefei,Anhui 230031,China;School of Pharmacy,Anhui University of Traditional Chinese Medicine,Hefei,Anhui 230012,China)

机构地区：[1]安徽中医药大学第一附属医院药学部,安徽合肥230031 [2]安徽中医药大学药学院,安徽合肥230012

出　　处：《安徽医药》2025年第1期183-188,F0003,共7页Anhui Medical and Pharmaceutical Journal

摘　　要：目的分析某三甲中医院治疗新型冠状病毒感染(COVID-19)中药处方信息,为中医药治疗COVID-19和中药师的审方提供参考。方法收集并整理安徽中医药大学第一附属医院2022年12月确诊为COVID-19后接受中药处方治疗病人的处方资料,通过Excel表录入整理处方相关信息数据,建立治疗COVID-19的中药处方数据库,统计治疗COVID-19的中药处方相关信息,探究用于COVID-19治疗的中药方剂信息,挖掘方剂中药物配伍的关联模式,并应用聚类方法揭示用药规律。结果共纳入99张治疗COVID-19的中药处方,经分析,处方病人年龄在60岁及以上的人数最多,占40.40%;在中药治疗COVID-19的方案中,处方包含11~15种药材的频率最高,占比达48.49%;用药剂量在10~15 g的处方频率最高,占比达到66.67%;中药处方用药天数多在3 d以内;中药处方所花金额小于100元的处方占66%;对中药使用频率进行统计发现补益药使用最多,占22%,其次是清热药18.5%;在分析用于COVID-19的中药处方中,甘草、白术、苦杏仁、茯苓、陈皮、柴胡和黄芩等药材的使用频率较高。其中,黄芩与甘草、柴胡以及半夏的组合在处方中尤为常见。这些药材的配伍显示出较高的关联性,表明它们在治疗中往往被一起使用。结论黄芩、甘草、柴胡和半夏在COVID-19的中药治疗中存在协同应用模式;在治疗中药处方中补益药、清热药、解表药使用频率最高,相关药物与类方组合为诊治COVID-19提供依据和参考。Objective To analyze the prescription information of The First Affiliated Hospital of Anhui University of Traditional Chinese Medicine for the treatment of Coronavirus Disease 2019(COVID-19)in December 2022 to provide reference for Chinese medicine treatment of COVID-19 and the review of prescriptions by Chinese pharmacists.Methods Information on prescriptions of traditional Chinese medicine used by outpatients with confirmed COVID-19 at Anhui Provincial Hospital of Traditional Chinese Medicine was collected,and Excel sheets were entered to organize prescription-related information data to establish a database of prescriptions of traditional Chinese medicine for the treatment of COVID-19.The relevant information of TCM prescriptions for the treatment of COVID-19 was collected.The information of traditional Chinese medicine formulations used in the treatment of COVID-19 was explored,the association pattern of drug compatibility in the formulations was excavated,and clustering methods were used to reveal drug use rules.Results Among the prescriptions of 99 patients with COVID-19 treated with Chinese medicine,the age of the patients was mainly concentrated above 60 years old,accounting for 40.40%;the frequency of prescriptions containing 11 to 15 kinds of medicinal materials in the treatment of COVID-19 with TCM was the highest,accounting for 48.49%;the dosage of Chinese medicine decoction prescriptions was mainly concentrated in the dosage of 10-15g,accounting for 66.67%.The days of TCM prescription were mostly within 3 days;the amount of Chinese medicine prescriptions spent less than 100 yuan accounted for 66%;according to the statistics of the frequency of use of TCM,the use of tonifying drugs was the most,accounting for 22%,followed by heat-clearing drugs 18.5%.In the analysis of TCM prescriptions for COVID-19,Glycyrrhiza glabra,Rhizoma Atractylodis Macrocephala,Bitter Almond,Poria,Chen Pi,Radix Bupleurum,Scutellaria were used more frequently.Among them,the combination of Scutellaria baicalensis with Glycyrrhiza

关 键 词：新型冠状病毒感染 中药 处方分析 用药规律 关联规则 

分 类 号：R288[医药卫生—中药学]