艾司氯胺酮复合丙泊酚麻醉诱导在无痛胃肠镜检查中的应用效果  

Application effects of anesthesia induction of Esketamine combined with Propofol in painless gastrointestinal endoscopy

作　　者：张凌宇[1] 张庆洪[1] 马达 ZHANG Lingyu;ZHANG Qinghong;MA Da(Department of Anesthesiology of the First Affiliated Hospital of Xiamen University,Xiamen 361000 Fujian,China)

机构地区：[1]厦门大学附属第一医院麻醉科,福建厦门361000

出　　处：《中国民康医学》2024年第24期57-59,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:观察艾司氯胺酮复合丙泊酚麻醉诱导在无痛胃肠镜检查中的应用效果。方法:回顾性分析2023年1—12月于该院行无痛胃肠镜检查者94名的临床资料,按照麻醉诱导方式不同将其分为观察组与对照组各47名。对照组采用丙泊酚麻醉诱导,观察组采用艾司氯胺酮复合丙泊酚麻醉诱导,比较两组麻醉起效时间、恢复室停留时间、离院时麻醉后出院评分量表(PADSS)评分、不同时间[麻醉诱导前(T_(0))、麻醉诱导注药后即刻(T_(1))、入镜至回肠末端(T_(2))、苏醒即刻(T_(3))]体征指标[平均动脉压(MAP)、心率、血氧饱和度(SpO_(2))]水平,以及不良反应发生率。结果:观察组麻醉起效时间短于对照组,差异有统计学意义(P<0.05);T_(1)、T_(2)时,两组MAP、心率均低于T_(0)时,但观察组高于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率为8.51%,明显低于对照组的23.40%,差异有统计学意义(P<0.05);两组恢复室停留时间、离院时PADSS评分以及不同时间(T_(0)、T_(1)、T_(2)、T_(3))SpO_(2)水平比较,差异均无统计学意义(P>0.05)。结论:艾司氯胺酮复合丙泊酚麻醉诱导应用于无痛胃肠镜检查可缩短麻醉起效时间,提高MAP和心率水平,以及降低不良反应发生率,效果优于单纯丙泊酚麻醉诱导。Objective:To observe application effects of anesthesia induction of Esketamine combined with Propofol in painless gastrointestinal endoscopy.Methods:The clinical data of 94 patients who underwent painless gastrointestinal endoscopy in this hospital from January December 2023 were retrospectively analyzed.According to different anesthesia induction methods,they were divided into observation group and control group,47 cases in each group.The control group was induced by Propofol anesthesia,while the observation group was induced by Esketamine combined with Propofol anesthesia.The anesthesia onset time,the recovery room stay time,the post-anesthesia discharge score scale(PADSS)score at the time of discharge from the hospital,the vital sign indicators[mean arterial pressure(MAP),heart rate,blood oxygen saturation(SpO_(2))]levels at different times[before anesthesia induction(T_(0)),immediately after anesthesia induction(T_(1)),mirror into the end of the ileum(T_(2)),immediately after awakening(T_(3))]and the incidence of adverse reactions were compared between the two groups.Results:The anesthesia onset time in the observation group was shorter than that in the control group,and the difference was statistically significant(P<0.05).At T_(1)and T_(2),the MAP and heart rate levels of the two groups were lower than those at T_(0),but those in the observation group were higher than those in the control group,and the differences were statistically significant(P<0.05).The incidence of adverse reactions in the observation group was 8.51%,which was significantly lower than 23.40%in the control group,and the difference was statistically significant(P<0.05).There were no significant differences in the recovery room stay time,the PADSS score at discharge and the SpO_(2)level at different time(T_(0),T_(1),T_(2),T_(3))between the two groups(P>0.05).Conclusions:The anesthesia induction of Esketamine combined with Propofol in painless gastrointestinal endoscopy can shorten the anesthesia onset time,improve the levels of MAP and hear

关 键 词：艾司氯胺酮 丙泊酚 无痛胃肠镜检查 平均动脉压 心率 血氧饱和度 不良反应 

分 类 号：R614.2[医药卫生—麻醉学]