富血小板血浆联合超短波治疗膝骨关节炎的临床效果  

Clinical Effects of Platelet-Rich Plasma Combined with Ultra-shortWave in the Treatment of Knee Osteoarthritis

作　　者：殷凡彪 张海燕[1] 尹海庆[2] 郭美莉[1] 程晓飞 贾瑞莉 钞宝香 YIN Fanbiao;ZHANG Haiyan;YIN Haiqing;GUO Meili;CHENG Xiaofei;JIA Ruili;CHAO Baoxiang(Department of Rehabilitation,Henan Hongli Hospital,Xinxiang 453400,China;Department of Oncology,Henan Hongli Hospital,Xinxiang 453400,China)

机构地区：[1]河南宏力医院康复科,河南新乡453400 [2]河南宏力医院肿瘤内科,河南新乡453400

出　　处：《河南医学研究》2024年第24期4503-4506,共4页Henan Medical Research

摘　　要：目的 观察富血小板血浆(PRP)联合超短波治疗膝骨关节炎的临床效果及安全性。方法 选取2021年9月至2022年9月在河南宏力医院治疗的60例膝骨关节炎患者,按随机数表法分为观察组和对照组,给予观察组PRP膝关节内注射联合超短波治疗,给予对照组超短波治疗,比较治疗后3个月两组患者的西安大略和麦克马斯特大学骨关节炎指数(WOMAC)、视觉模拟评分(VAS)、晨僵时间、膝关节功能恢复情况及不良反应。结果 观察组膝关节功能恢复的总有效率93.3%,高于对照组的70.0%(P=0.043)。治疗3个月后观察组及对照组VAS评分及WOMAC评分低于治疗前(P<0.001),且观察组低于对照组(P<0.001);两组晨僵时间均短于治疗前(P<0.001),观察组短于对照组(P=0.027);观察组5例患者出现一过性膝关节轻度肿胀加重。结论 PRP联合超短波治疗膝骨关节炎的效果显著,能很好地缓解疼痛,改善患者膝关节功能,且不良反应轻微。Objective To observe the clinical efficacy and safety of platelet-rich plasma(PRP)combined with ultra-short wave in the treatment of knee osteoarthritis.Methods From September 2021 to September 2022 in Henan Hongli Hospital,a total of 60 patients with knee osteoarthritis were selected,these patients were divided into control group and observation group according to random number table method.The observation group was given PRP intra-knee injection combined with ultra-short wave therapy,whereas the control group was given ultra-short wave therapy only.Western Ontario and McMaster University osteoarthritis index(WOMAC),visual analogue scale(VAS),morning stiffness time,knee functional recovery and adverse reactions were compared between the two groups after 3 months treatments.Results The total effective rate of knee functional recovery was 93.3%in the observation group,which was higher than that of in the control group(70.0%)(P=0.043).After three months treatments,both VAS score and WOMAC score were lower than before treatments(P<0.001),and the observation group were lower than those in the control group(P<0.001).The morning stiffness time of the two groups was shorter than before treatments(P<0.001),and the observation group was shorter than that of the control group(P=0.027).In the observation group,5 patients had transient mild swelling of knee joint.Conclusion PRP combined with ultra-short wave is effective in the treatment of knee osteoarthritis,which can effectively relieve pain and improve knee joint function with slight side effects.

关 键 词：膝骨关节炎 富血小板血浆 超短波 

分 类 号：R684.3[医药卫生—骨科学]