血清OPN、25(OH)D、CTGF水平预测产后盆底功能障碍的价值观察  

Observation on the value of serum OPN,25(OH)D and CTFG levels in predicting postpartum pelvic floor dysfunction

作　　者：郝晓玲 邢忠兴 侯艳丽 Hao Xiaoling;Xing Zhongxing;Hou Yanli(Obstetrics and Gynecology Department of Cangzhou Maternal and Child Health Hospital,Cangzhou 061000,Hebei)

机构地区：[1]沧州市妇幼保健院产科,河北沧州061000

出　　处：《现代科学仪器》2024年第6期72-76,共5页Modern Scientific Instruments

基　　金：河北省2019年度医学科学研究重点课题计划项目(项目编号:20191247)。

摘　　要：目的:探讨血清骨桥蛋白(OPN)、25羟维生素[25(OH)D]、结缔组织生长因子(CTGF)水平预测产后盆底功能障碍(PFD)的价值。方法:回顾性选取2019年8月至2022年8月收治的85例产后PFD患者与85名正常产妇。分析产后发生PFD的影响因素及OPN、25(OH)D、CTGF水平预测产后PFD的价值。结果:ROC结果显示,OPN、25(OH)D、CTGF水平预测产后PFD的AUC分别为0.883、0.841、0.934(P<0.05)。结论:发生产后PFD的患者OPN、CTGF较高,25(OH)D较低,在产后PFD预测中均有一定价值。Objective:To investigate the value of serum osteobridging protein(OPN),25 hydroxyvitamin[25(OH)D],and connective tissue growth factor(CTGF)levels in predicting postpartum pelvic floor dysfunction(PFD).Methods:Eighty-five patients with postpartum PFD admitted from August 2019 to August 2022 were retrospectively selected with 85 normal women.Factors influencing the occurrence of PFD in the postpartum period and the value of OPN,25(OH)D,and CTGF levels in predicting postpartum PFD were analyzed.Results:The ROC results showed that the AUCs of OPN,25(OH)D,and CTGF levels to predict postpartum PFD were 0.883,0.841,and 0.934,respectively(P<0.05).Conclusion:Patients who developed postpartum PFD had higher OPN,CTGF,and lower 25(OH)D,all of which are valuable in the prediction of postpartum PFD.

关 键 词：盆底功能障碍 骨桥蛋白 25羟维生素 结缔组织生长因子 

分 类 号：R715[医药卫生—妇产科学]