超声评估肾动脉血流阻力指数在糖尿病肾病鉴别中的应用  

Application of ultrasound evaluation of renal artery blood flow resistance index in differential diagnosis of diabetic kidney disease

作　　者：史家安 张洪莉 王艳君 秦朗 茹莹 钱瑾 马续祥 Shi Jiaan;Zhang Hongli;Wang Yanjun;Qin Lang;Ru Ying;Qian Jin;Ma Xuxiang(Department ofNephrology,Fengyang County People’s Hospital,Chuzhou233100,Anhui,China;Ultrasound Department,FengyangCounty People’s Hospital,Chuzhou233100,Anhui,China;Department ofNephrology,The Second Affiliated Hospital of BengbuMedical University,Bengbu233040,Anhui,China)

机构地区：[1]凤阳县人民医院肾内科,安徽滁州233100 [2]凤阳县人民医院超声科,安徽滁州233100 [3]蚌埠医学院第二附属医院肾内科,安徽蚌埠233040

出　　处：《现代科学仪器》2024年第6期159-163,共5页Modern Scientific Instruments

基　　金：2022年度蚌埠医学院厅级重点实验室开放课题(编号:AHTT2022B004)。

摘　　要：目的:探究多普勒超声评估肾动脉血流阻力指数(RI)在糖尿病肾病(DKD)与无DKD鉴别中的应用。方法:回顾性分析84例疑似DKD的2型糖尿病(T2DM)患者临床资料,均行多普勒超声检查,分为DKD组44例和无DKD组40例。结果:DKD组RI值均高于无DKD组(P均<0.05);logistics回归分析显示,IMT、UA、BUN、SCr、β2-MG、HbAlc、CysC是DKD发生的独立危险因素(P均<0.05);RI值鉴定DKD的AUC为0.865。结论超声检测的肾动脉RI值对DKD具有较高的鉴别效能。Objective:To explore the application of Doppler ultrasound in evaluating renal artery blood flow resistance index(RI)in the differential diagnosis of diabetic kidney disease(DKD)and non-DKD.Methods:The clinical data of 84 patients with type 2 diabetes mellitus(T2DM)who were suspected with DKD were retrospectively analyzed.All patients underwent Doppler ultrasound examination and were divided into DKD group(44 cases)and non-DKD group(40 cases).Results:The RI values of the main renal artery were higher in DKD group than those in non-DKD group(all P<0.05).Logistics regression analysis showed that IMT,UA,BUN,SCr,β2-MG,HbAlc and CysC were independent risk factors for DKD(all P<0.05).The AUC of RI value in identifying DKD was 0.865.Conclusion:The renal artery RI value detected by ultrasonography has a high effective in differentiating DKD.

关 键 词：糖尿病肾病 多普勒超声 血流阻力指数 危险因素 鉴别价值 

分 类 号：R692.9[医药卫生—泌尿科学] R445.1[医药卫生—外科学] R587.2[医药卫生—临床医学]