气道廓清技术联合支气管镜肺泡灌洗治疗老年性坠积性肺炎的优效性  

Study on the optimal efficiency of airway clearance technique combined with bronchoscopic bronchoalveolar lavage in elderly patients with hypostatic pneumonia

作　　者：陈丹 李大权 孔晋亮[2] 温柳云 李琳 CHEN Dan;LI Daquan;KONG Jinliang;WEN Liuyun;LI Lin(Department of Respiratory and Critical Care Medicine,Workers'Hospital of Guangxi Zhuang Autonomous Region,Nanning 530021,Guangxi,China;Ward 3 of Respiratory and Critical Care Medicine Department,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021,Guangxi,China)

机构地区：[1]广西壮族自治区工人医院呼吸与危重症医学科,广西南宁530021 [2]广西医科大学第一附属医院呼吸与危重症医学科三病区,广西南宁530021

出　　处：《右江医学》2024年第11期983-988,共6页Chinese Youjiang Medical Journal

基　　金：广西壮族自治区卫生健康委自筹经费科研课题(Z-A20230415)。

摘　　要：目的探讨气道廓清技术联合支气管镜肺泡灌洗在老年性坠积性肺炎中应用的优效性。方法选取2023年1月—2024年2月在广西壮族自治区工人医院诊治的老年性坠积性肺炎患者112名进行前瞻性研究,采用单纯随机法分成两组,实验组(n=55)采用气道廓清技术联合支气管镜肺泡灌洗治疗,对照组(n=57)采用单纯支气管镜肺泡灌洗治疗。收集老年性坠积性肺炎患者相关资料,对比两种治疗方法的临床疗效。结果实验组与对照组患者基础情况(年龄、性别、营养评估、生活自理能力、肺炎评价、半定量咳嗽能力评价)对比分析差异无统计学意义(P>0.05)。实验组治疗后72小时症状好转率、72小时生命征和肺部CT检查结果好转率显著优于对照组,差异有统计学意义(P<0.05)。实验组血C反应蛋白在治疗后显著低于对照组,差异有统计学意义(P<0.05)。两组发病期间抗生素使用率差异有统计学意义(P<0.05)。两组治疗后痰液和肺泡灌洗液病原学差异无统计学意义(P>0.05)。结论气道廓清技术联合支气管镜肺泡灌洗较单纯支气管镜肺泡灌洗在治疗老年性坠积性肺炎中优效性明显。Objective To explore the optimal efficiency of airway clearance technology combined with bronchoscopic bronchoalveolar lavage in elderly patients with hypostatic pneumonia.Methods A prospective study was conducted on 112 elderly patients with hypostatic pneumonia who were treated at the Workers'Hospital of Guangxi Zhuang Autonomous Region from January 2023 to February 2024.All patients were divided into two groups by simple random method.Experimental group(n=55)were treated with airway clearance technology combined with bronchoscopy bronchoalveolar lavage,while control group(n=57)were treated with simple bronchoscopy bronchoalveolar lavage.Relevant data on elderly patients with hypostatic pneumonia were collected,and the clinical efficacy of the two treatment methods was compared.Results There was no statistically significant difference in basic conditions(age,gender,nutritional assessment,self-care ability,pneumonia evaluation,semi-quantitative cough ability evaluation)between the experimental group and the control group(P>0.05).The improvement rate of symptoms,vital signs,and lung CT examination results at 72 hours after treatment in the experimental group were significantly better than those in the control group,and difference was statistically significant(P<0.05).Serum C-reactive protein in the experimental group was significantly lower than that in the control group after treatment,and the difference was statistically significant(P<0.05).There was statistically significant difference in the use of antibiotics between the two groups during the onset of the disease(P<0.05).There was no statistically significant difference in the etiology of sputum and bronchoalveolar lavage fluid between the two groups after treatment(P>0.05).Conclusion Airway clearance technology combined with bronchoscopic bronchoalveolar lavage is more effective compared with simple bronchoscopic lung lavage in the treatment of elderly patients with hypostatic pneumonia.

关 键 词：气道廓清技术 支气管镜肺泡灌洗 坠积性肺炎 老年 

分 类 号：R563.1[医药卫生—呼吸系统]