基于高熵化合物的无酶葡萄糖传感器的制备与性能研究  

Preparation and performance study of enzyme-free glucose sensors based on high-entropy compounds

作　　者：吕炎文 卢玉婷 许可莹 张宏伟 LV Yanwen;LU Yuting;XU Keying;ZHANG Hongwei(College of Materials Science and Engineering,Wuhan Textile University,Wuhan 430073,China;College of Textile and Engineering,Wuhan Textile University,Wuhan 430073,China)

机构地区：[1]武汉纺织大学材料科学与工程学院,武汉430073 [2]武汉纺织大学纺织科学与工程学院,武汉430073

出　　处：《纺织工程学报》2024年第6期48-54,共7页JOURNAL OF ADVANCED TEXTILE ENGINEERING

基　　金：武汉纺织大学大学生创新创业训练计划项目。

摘　　要：葡萄糖的高效检测在医疗诊断、食品质量监测和环境监测等领域具有重要意义。采用溶剂热和煅烧相结合的方法,制备了三种高熵化化合物(高熵氢氧化物、高熵氧化物和高熵硫化合物)用于无酶葡萄糖传感器。通过X射线衍射与扫描电子显微镜对其结构和形貌进行表征,并使用循环伏安法和计时电流法测试葡萄糖传感器电极的电化学性能,研究其对葡萄糖的电催化氧化活性。实验结果表明:基于高熵氧化物构建的无酶葡萄糖传感器对葡萄糖检测线性范围宽(0.4~10 mmol/L,R2可达到0.9963),检测灵敏度高(可达到3.11μA·mmol·L^(-1)·cm^(-2)),而且对血液中葡萄糖共存物质表现出良好的抗干扰性能,表明高熵化合物在无酶葡萄糖传感器开发中具有潜在的应用价值。It is of great significance for the rapid and effective detection of glucose in medical diagnosis,food quality monitoring,environmental monitoring,and other related fields.three high-entropy compounds(highentropy hydroxides,high-entropy oxides,and high-entropy sulfides)were prepared using a combination of solvothermal and calcination methods for enzyme-free glucose sensors.The structures and morphologies were characterized by X-ray diffraction and scanning electron microscopy.The electrochemical performance of the glucose sensor electrodes was tested using cyclic voltammetry and chronoamperometry to study their electrocatalytic oxidation activity towards glucose.Experimental results show that the enzyme-free glucose sensor based on high-entropy oxides has a wide linear range for glucose detection(0.4-10 mmol/L,with an R2 value of up to 0.9963),high detection sensitivity(up to 3.11μA·mmol·L^(-1)·cm^(-2)),and excellent anti-interference performance towards coexisting substances in blood glucose,indicating the potential application of high-entropy compounds in the development of enzyme-free glucose sensors.

关 键 词：高熵化合物 葡萄糖 传感器 电催化活性 无酶检测 

分 类 号：O657.1[理学—分析化学]