2023年STOPP/START标准解读  

Interpretation of the 2023 STOPP/START criteria

作　　者：刘子祺 张帆 李成敏 田英超 杜艳红 付晓菲 雷宁 LIU Zi-qi;ZHANG Fan;LI Cheng-min;TIAN Ying-chao;DU Yan-hong;FU Xiao-fei;LEI Ning(Characteristic Medical Center of the Rocket Force,People’s Liberation Army,Beijing 100088)

机构地区：[1]火箭军特色医学中心,北京100088

出　　处：《中南药学》2024年第12期3394-3402,共9页Central South Pharmacy

基　　金：部委级保健专项科研课题(No.20BJZ14)。

摘　　要：目的 对2023年第三版老年人潜在不适当处方筛查工具(STOPP)/处方遗漏筛查工具(START)标准进行详细解读,从而优化药物治疗并最大限度地减少老年人(特别是患有多种疾病和使用多种药物的老年人)的药物不良反应/事件。方法 通过与2014年第二版STOPP/START标准进行比对,对比对结果进行逐条分析,对差异进行总结。结果 第三版STOPP/START标准共190个条目,其中STOPP标准新增54个条目,删除4个条目,修订31个条目。START标准新增指示性药物、凝血系统、肾脏系统3个部分/系统,新增24个条目,删除3个条目,修订20个条目。结论 2023年第三版STOPP/START标准提升了准确性和实用性,更有利于帮助临床医师和药师在常规药物审查期间发现和预防更多的不良药物-药物和药物-疾病相互作用,但要在临床诊疗中发挥更大的作用,还需先进的技术支持及多个部门通力合作。Objective To optimize medication use and minimize adverse drug events during medication review in the elderly,particularly for those with various diseases and taking several medicines through a detailed interpretation of screening tool of older persons’ prescriptions/screening tool to alert to right treatment (STOPP/START) criteria (version 3) in 2023.Methods We compared STOPP/START criteria of 2014 (version 2) with version 3 of 2023 and summarized the differences.Results STOPP/START version 3 consisted of 190 criteria,54 of which were newly added,4 of which criteria were removed,and 31 revised.Meanwhile,3 parts /systems (indicated drugs,coagulation system,and the renal system) and 24 items were added,3 were removed,and 20 revised in the START new version.Conclusion The 2023 STOPP/START criteriaare more accurate and useful,facilitating clinicians and pharmacists in detecting and preventing adverse events and their consequences during routine review.Further technical support and cooperation between departments are needed.

关 键 词：STOPP/START标准 潜在不适当用药 老年人 合理用药 

分 类 号：R95[医药卫生—药学]