泰安地区510例呼吸道过敏患儿吸入性过敏原检测结果分析  

Analysis of inhalation allergen detection results in 510 children with respiratory allergies in Tai'an region

作　　者：刘路 LIU Lu(Department of Clinical Laboratory,Tai'an Maternal and Child Health Hospital,Shangdong Tai'an 271000)

机构地区：[1]泰安市妇幼保健院检验科,山东泰安271000

出　　处：《医学检验与临床》2024年第11期33-36,61,共5页Medical Laboratory Science and Clinics

摘　　要：目的:探讨泰安地区呼吸道过敏患儿吸入性过敏原的分布特征,为该群体的临床诊疗提供理论依据。方法:选取2021年9月-2023年9月于泰安市妇幼保健院就诊的510例呼吸道过敏患儿为研究对象,采用免疫印迹法检测10种吸入性过敏原特异性抗体IgE(sIgE)并统计分析其检测结果。结果:510例患儿吸入性过敏原总阳性率为58.63%,其中阳性率最高的是屋尘螨/粉尘螨(33.92%),其次是霉菌组合(16.67%)和艾蒿(10.59%);男、女患儿之间吸入性过敏原总阳性率无明显差异(P>0.05);不同年龄组吸入性过敏原总阳性率、屋尘螨/粉尘螨、猫毛皮屑阳性率差异有统计学意义(P<0.05);夏季吸入性过敏原阳性率最高(72.00%),不同季节过敏原总阳性率、屋尘螨/粉尘螨、艾蒿、草、霉菌组合及树花粉组合阳性率差异均具有统计学意义(P<0.05)。结论:泰安地区呼吸道过敏患儿常见的吸入性过敏原是屋尘螨/粉尘螨、霉菌组合和艾蒿,吸入性过敏原分布差异与年龄和季节有关。Objective:To explore the distribution characteristics of inhaled allergens in children with respiratory allergies in Tai'an region,and to provide a theoretical basis for clinical diagnosis and treatment of this population.Methods:From September 2021 to September 2023,510 children with respiratory allergies who visited Tai'an Maternal and Child Health Hospital were selected,10 types of inhaled allergen IgE(sIgE)antibodies were detected by immunoblotting assay and statistically analyze the detection results.Results:The total positive rate of inhalation allergens in 510 children was 58.63%,the highest positive rate was the house dust mite/dust mite(33.92%),followed by the mold combination(16.67%)and mugwort(10.59%);There was no significant difference in the total positive rate of inhaled allergens between male and female children(P>0.05);There were statistically significant difference in the total positive rate of inhaled allergens,house dust mites/dust mites,and cat dander among different age groups(P<0.05);The highest positive rate of inhaled allergens in summer(72.00%),there were statistically significant differences in the total positive rates of allergens,house dust mites/dust mites,mugwort,humulus,mold combinations,and tree pollen combinations in different seasons(P<0.05).Conclusion:The common inhalation allergens in children with respiratory allergies in Tai'an region are house dust mites/dust mites,mold combinations,and mugwort,the distribution differences of inhalation allergens are related to age and seasons.

关 键 词：吸入性过敏原 儿童 呼吸道过敏 

分 类 号：R725.6[医药卫生—儿科]