神经内镜微创手术与小骨窗开颅血肿清除术治疗高血压脑出血的临床效果对比  

Clinical Effect of Minimally Invasive Neuroendoscopic Surgery and Small Bone Window Craniotomy Hematoma Removal in the Treatment of Hypertensive Cerebral Hemorrhage

作　　者：刘少政 Liu Shaozheng(Guangxi Zhuang Autonomous Region People's Hospital,Nanning 530000,Guangxi Zhuang Autonomous Region,China)

机构地区：[1]广西壮族自治区人民医院,广西壮族自治区南宁530000

出　　处：《中外医药研究》2024年第33期6-8,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:对比神经内镜微创手术与小骨窗开颅血肿清除术治疗高血压脑出血的效果。方法:选取2021年7月—2023年6月广西壮族自治区人民医院收治的高血压脑出血患者68例为研究对象,随机分为试验组和对照组,各34例。对照组使用小骨窗开颅血肿清除术治疗,试验组使用神经内镜微创手术治疗。对比两组颅脑损伤指标、脑血流动力学指标、神经损伤情况及并发症发生情况。结果:干预前,两组髓鞘碱性蛋白(MBP)、神经元特异性烯醇化酶(NSE)水平对比,无统计学差异(P>0.05);干预后,两组MBP、NSE水平降低,试验组低于对照组(P<0.05)。干预前,两组脑动脉舒张末期峰值流速(Vd)、脑动脉收缩末期峰值流速(Vp)水平对比,无统计学差异(P>0.05);干预后,两组Vd、Vp水平升高,试验组高于对照组(P<0.05)。干预前,两组功能独立评价量表(FIM)、格拉斯哥昏迷评分法(GCS)、美国国立卫生院卒中量表(NIHSS)评分对比,无统计学差异(P>0.05);干预后,两组FIM、GCS评分升高,NIHSS评分降低,试验组优于对照组(P<0.05)。试验组并发症总发生率低于对照组(P=0.0239)。结论:对高血压脑出血患者使用神经内镜微创手术进行治疗,可改善患者颅脑损伤情况,保护脑功能,降低神经损伤,且治疗安全性较高。Objective:To compare the effect of minimally invasive neuroendoscopic surgery and small bone window craniotomy hematoma removal in the treatment of hypertensive cerebral hemorrhage.Methods:Sixty-eight patients with hypertensive cerebral hemorrhage admitted to Guangxi Zhuang Autonomous Region People's Hospital from July 2021 to June 2023 were selected as the study objects,and were randomly divided into experimental group and control group,with thirty-four patients in each group.The control group was treated with small bone window craniotomy hematoma removal,and the experimental group was treated with neuroendoscopic minimally invasive surgery.The indexes of craniocerebral injury,cerebral hemodynamics,nerve injury and complications were compared between the two groups.Results:Before intervention,there were no significant differences in myelin basic protein(MBP)and neuron-specific enolase(NSE)levels between the two groups(P>0.05);after the intervention,the levels of MBP and NSE in the experimental group were lower than those in the control group(P<0.05).Before intervention,there was no significant difference in the end-diastolic peak flow velocity(Vd)and end-systolic peak flow velocity(Vp)between the two groups(P>0.05);after intervention,the levels of Vd and Vp in the experimental group were higher than those in the control group(P<0.05).Before intervention,there was no significant difference in the scores of independent functional assessment scale(FIM),Glasgow coma scale(GCS)and national institutes of health stroke scale(NIHSS)between the two groups(P>0.05);after intervention,FIM and GCS scores were increased,NIHSS scores were decreased,and the experimental group was better than the control group(P<0.05).The total complication rate of experimental group was lower than that of control group(P=0.0239).Conclusion:The use of neuroendoscopic minimally invasive surgery in the treatment of hypertensive cerebral hemorrhage patients can improve the condition of craniocerebral injury,protect brain function,reduce nerve injur

关 键 词：高血压 脑出血 神经内镜微创手术 小骨窗开颅血肿清除术 

分 类 号：R651.1[医药卫生—外科学]