玫瑰痤疮与其他皮肤疾病的皮肤镜检查结果比较分析  

Comparative Analysis of Skin Microscopy Results Between Rosacea and Other Skin Diseases

作　　者：任贵珍 孙瑜[1] 于继鹏 许俨 REN Gui-zhen;SUN Yu;YU Ji-peng;XU Yan(Dermatology Department of Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital,Tianjin 300120)

机构地区：[1]天津市中医药研究院附属医院皮肤科,天津300120

出　　处：《中国医疗器械信息》2024年第24期17-19,46,共4页China Medical Device Information

摘　　要：目的:研究比较玫瑰痤疮与其他皮肤疾病的皮肤镜检查结果。方法:选取2021年12月~2023年12月来自天津中医药研究院附属医院门诊皮肤科就诊患者260例。其中160例玫瑰痤疮患者为研究组,100例其他皮肤疾病(痤疮、红斑狼疮、脂溢性皮炎等)患者为对照组。两组患者均行皮肤镜检查,比较两组皮肤镜检查结果差异,以确诊玫瑰痤疮为因变量对两组差异性因素行多因素Logistic回归分析,最终计算皮肤镜对玫瑰痤疮的诊断效能。结果:研究组与对照组的血管形态(多角形血管、不典型血管)、背景颜色、血管排列、鳞屑、丘疹脓疱(有脓疱)、毛囊角栓(有毛囊周围油滴状晕、有毛囊周围白晕)、色素沉着、皮损位置(下颌、鼻部)比较,差异有统计学意义(P<0.05);多角形血管、背景颜色、血管排列、有脓疱、有毛囊周围油滴状晕、皮损位置位于鼻部是诊断为玫瑰痤疮的影响因素(P<0.05);皮肤镜对玫瑰痤疮的诊断敏感度为95.63%(152/160)、特异度为96.00%(96/100)、准确度为95.77%(249/260)、阳性预测值97.45%(153/157)、阴性预测值93.20%(96/103)。结论:玫瑰痤疮与其他皮肤疾病(痤疮、红斑狼疮、脂溢性皮炎等)在皮肤镜检查结果中存在多种差异,如多角形血管、网状血管排列等,可以行皮肤镜完成对玫瑰痤疮的鉴别诊断,有良好的诊断效能。Objective:To compare the results of skin microscopy examination between rosacea and other skin diseases.Methods:260 patients from the outpatient dermatology department of Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital were selected from December 2021 to December 2023.Among them,160 patients with rosacea were selected as the study group,and 100 patients with other skin diseases(acne,lupus erythematosus,seborrheic dermatitis,etc.)were selected as the control group.Both groups of patients underwent dermatoscopy examination,and the differences in dermatoscopy results between the two groups were compared.Multivariate Logistic regression analysis was performed on the differential factors between the two groups with confirmed rosacea as the dependent variable,and the diagnostic efficacy of dermatoscopy for rosacea was finally calculated.Results:There was a statistically significant difference(P<0.05)in the vascular morphology(polygonal vessels,atypical vessels),background color,vascular arrangement,scales,papules and pustules(with pustules),hair follicle horn plugs(with oil droplet like halos around hair follicles and white halos around hair follicles),pigmentation,and lesion location(mandible,nose)between the study group and the control group;The factors influencing the diagnosis of rosacea include polygonal blood vessels,background color,vascular arrangement,presence of pustules,oil droplet like halos around hair follicles,and the location of skin lesions on the nose(P<0.05);The sensitivity,specificity,accuracy,positive predictive value,and negative predictive value of dermatoscopy for the diagnosis of rosacea were 95.63%(152/160),96.00%(96/100),95.77%(249/260),97.45%(153/157),and 93.20%(96/103),respectively.Conclusion:There are various differences between rosacea and other skin diseases(acne,lupus erythematosus,seborrheic dermatitis,etc.)in the results of skin microscopy examination,such as polygonal blood vessels,reticular blood vessel arrangement,etc.This dermatoscopy can be used to complete th

关 键 词：玫瑰痤疮 痤疮 红斑狼疮 脂溢性皮炎 皮肤镜 鉴别诊断 

分 类 号：R758.734[医药卫生—皮肤病学与性病学]