基于“肾脑相济”理论探讨耳穴通过HPO轴治疗围绝经期失眠的机制  

Exploration of the Mechanism of Auricular Point Therapy for Perimenopausal Insomnia through HPO Axis Based on the Theory of“Kindey-Brain Coordination”

作　　者：崔嘉桐 任路[1] CUI Jiatong;REN Lu(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China)

机构地区：[1]辽宁中医药大学,辽宁沈阳110847

出　　处：《辽宁中医药大学学报》2025年第1期152-155,共4页Journal of Liaoning University of Traditional Chinese Medicine

基　　金：国家自然科学基金(82274665);辽宁省特聘教授项目(辽教发[2015]153号)。

摘　　要：围绝经期失眠症,又称为更年期失眠症,指女性在围绝经期即绝经前后的一段时期发生失眠症状。流行病学调查显示,围绝经期失眠症是严重困扰围绝经期妇女身心健康的重要问题之首。中医认为此病与肾虚造成“肾脑失济”,肾-天癸-冲任-胞宫轴功能衰退,脏腑机体失养,脑主精神意识功能失常有关。现代医学研究表明该病与下丘脑-垂体-卵巢轴(HPO轴)功能紊乱密切相关。文章基于“肾脑相济”理论以及HPO轴功能探讨耳穴治疗围绝经期失眠的机制,选取肾、内生殖器、神门、交感、内分泌5个穴位进行按压,以调整阴阳、调节HPO轴功能、使“肾脑相济”,从而达到治疗围绝经期失眠的目的,以期为临床治疗该病提供参考。Perimenopausal insomnia,also known as menopause insomnia,refers to women in the perimenopause that is,a period of time before and after menopause insomnia symptoms.According to the epidemiological survey,perimenopausal insomnia is the most important problem that seriously troubles the physical and mental health of perimenopausal women.Traditional Chinese medicine believes that this disease is related to kidney deficiency resulting in“kidney-brain dystunction”,kidney-Tiangui-Chongren-cellular palace axis function decline,Zang-Fu body dystrophy,brain master mental consciousness dysfunction.Modern medical research shows that the disease is closely related to the dysfunction of the HPO axis.Based on the theory of“kidney-brain coordination”and the function of HPO axis,this paper discusses the mechanism of auricular-point treatment for perimenopausal insomnia,and selects five acupoints of kidney,inner genitals,Shenmen,sympathy and endocrine to press,so as to adjust Yin and Yang,regulate the function of HPO axis,and make“kidney-brain coordination”,so as to achieve the purpose of treating perimenopausal insomnia.

关 键 词：“肾脑相济” 围绝经期失眠 HPO轴 耳穴 

分 类 号：R256.23[医药卫生—中医内科学]