AIDS血液透析患者抑郁影响因素分析  

Analysis of influencing factors of depression in AIDS hemodialysis patients

作　　者：周张青 崔龚臻 汪雪芬 刘涧 徐芳燕 李惠莉 ZHOU Zhangqing;CUI Gongzhen;WANG Xuefen;LIU Jian;XU Fangyan;LI Huili(Department of General Internal Medicine,Hangzhou Xixi Hospital,Hangzhou Sixth People’s Hospital,Hangzhou Xixi Hospital of Zhejiang Chinese Medicine University,Hangzhou 310023,Zhejiang,China)

机构地区：[1]杭州市西溪医院,杭州市第六人民医院,浙江中医药大学附属杭州西溪医院普内科,浙江杭州310023

出　　处：《中国现代医生》2024年第36期56-59,共4页China Modern Doctor

摘　　要：目的探讨人类免疫缺陷病毒(human immunodeficiency virus,HIV)/获得性免疫缺陷综合征(acquired immunodeficiency syndrome,AIDS)血液透析患者的抑郁和医疗社会支持的现状及医疗社会支持对抑郁的作用。方法收集2022年3月至2024年3月杭州市西溪医院HIV/AIDS血液透析患者80例。采用流调中心用抑郁自评量表(center for epidemiological survey-depression scale,CES-D)和医疗社会支持调查量表(medical social support scale,MOS-SSS)评估患者的抑郁和医疗社会支持情况。采用结构方程模型分析医疗社会支持与抑郁的关系。结果80例患者中42例(52.5%)患者出现抑郁症状(CES-D评分≥16分)。单因素分析结果显示,身体健康情况、抗病毒治疗情况、医疗社会支持对HIV抑郁有影响(P<0.05)。简单线性回归显示身体健康情况(95%CI:–9.901~–2.635)和抗病毒治疗情况(95%CI:–12.969~-3.394)是抑郁的影响因素(P<0.05)。医疗社会支持总分、有形支持维度、信息与情感支持维度、积极的社会互动维度、亲情支持维度与抑郁存在关联(P<0.001)。多重线性回归分析显示,医疗社会支持与抑郁呈负相关。医疗社会支持越高,抑郁发生率越低。结论AIDS血液透析患者抑郁症患病率偏高,医疗社会支持对缓解其病情有积极作用。Objective To explore the status quo of depression and medical-social support in human immunodeficiency virus(HIV)/acquired immunodeficiency syndrome(AIDS)hemodialysis patients,as well as the effect of medical-social support on depression.Methods A total of 80 HIV/AIDS hemodialysis patients from Xixi Hospital in Hangzhou from March 2022 to March 2024 were collected.Center for epidemiological survey-depression scale(CES-D)and medical social support scale(MOS-SSS)were used to assess patients for depression and medical social support.Structural equation model was used to analyze relationship between medical social support and depression.Results 42 of the 80 subjects(52.5%)had depressive symptoms(CES-D score≥16 points).The results of univariate analysis showed that health status,antiviral treatment status,medical social support had an impact on HIV depression(P<0.05).Simple linear regression showed that health status(95%CI:–9.901-–2.635)and antiviral treatment status(95%CI:–12.969-–3.394)were the influencing factors for depression(P<0.05).The total score of medical social support,tangible support dimension,information and emotional support dimension,positive social interaction dimension,emotional support dimension were associated with depression(P<0.001).Multiple linear regression analysis showed that medical social support was negatively associated with depression.The higher medical social support was the lower incidence of depression.Conclusion The prevalence of depression in AIDS hemodialysis patients is high,and medical social support has a positive effect on alleviating their condition.

关 键 词：人类免疫缺陷病毒/获得性免疫缺陷综合征 医疗社会支持 抑郁 结构方程模型 血液透析 

分 类 号：R512.91[医药卫生—内科学]