二陈汤合苏子降气汤加减联合穴位埋线治疗痰湿蕴肺型慢性阻塞性肺疾病的临床疗效观察  

Clinical observation on the treatment of chronic obstructive pulmonary disease with phlegm dampness accumulation syndrome by modified Erchen Decoction and Suzi Jiangqi Decoction combined with acupoint thread-embedding

作　　者：梁杰斌 马林 曹洪铭 黄均贤 邓铭俊 LIANG Jie-bin;MA Lin;CAO Hong-ming(Chen Xinghai Integrated Traditional Chinese and Western Medicine Hospital,Zhongshan 528415,China)

机构地区：[1]中山陈星海中西医结合医院,528415

出　　处：《中国实用医药》2024年第23期135-138,共4页China Practical Medicine

摘　　要：目的探讨二陈汤合苏子降气汤加减联合穴位埋线治疗痰湿蕴肺型慢性阻塞性肺疾病(COPD)患者的临床疗效。方法选取300例痰湿蕴肺型COPD患者为研究对象,按照随机数字表法分为观察组(n=150)和对照组(n=150)。对照组予以常规治疗,观察组以常规治疗方案为基础加用中药方剂二陈汤合苏子降气汤加减,并联合穴位埋线治疗。比较两组患者治疗前后中医证候积分(咳嗽、喘息、胸闷),动脉血气分析指标[动脉血二氧化碳分压(PaCO_(2))、动脉血氧分压(PaO_(2))],肺功能指标[第1秒用力呼气容积(FEV1)、用力肺活量(FVC)、最大呼气流量(PEF)]及临床疗效。结果观察组总有效率93.33%明显高于对照组的73.33%,差异性明显(P<0.05)。治疗后,两组患者中医证候积分均较治疗前明显下降,且观察组咳嗽、喘息、胸闷积分分别为(0.80±0.09)、(1.02±0.13)、(0.19±0.15)分,均明显低于对照组的(1.32±0.14)、(2.10±0.22)、(0.70±0.08)分,差异性明显(P<0.05)。治疗后,观察组PaO_(2)为(80.46±8.12)mm Hg(1 mm Hg=0.133 kPa)、PaCO_(2)为(35.28±3.61)mm Hg,对照组PaO_(2)为(69.11±7.01)mm Hg、PaCO_(2)为(44.86±4.60)mm Hg。与治疗前比较,治疗后两组患者PaCO_(2)均显著降低,PaO_(2)均显著升高,且与对照组比较,观察组PaCO_(2)更低,PaO_(2)更高,差异性明显(P<0.05)。与治疗前比较,治疗后两组患者FEV1、FVC、PEF均显著提升,且观察组FEV1(3.21±0.33)L、PEF(455.12±46.10)L/min、FVC(3.61±0.37)L明显高于对照组的(2.32±0.23)L、(398.25±40.28)L/min、(3.06±0.31)L,差异性明显(P<0.05)。结论二陈汤合苏子降气汤加减联合穴位埋线治疗痰湿蕴肺型COPD患者的临床疗效显著,值得临床应用。Objective To explore the clinical efficacy of modified Erchen Decoction and Suzi Jiangqi Decoction combined with acupoint thread-embedding in the treatment of chronic obstructive pulmonary disease(COPD)with phlegm dampness accumulation syndrome.Methods 300 cases of COPD with phlegm dampness accumulation syndrome were selected as the research subjects.According to the random number table method,they were divided into an observation group(n=150)and a control group(n=150).The patients of the control group received conventional therapy,while the patients of the observation group were treated with modified Erchen Decoction and Suzi Jiangqi Decoction combined with acupoint thread-embedding on the basis of the conventional therapy.Both groups were compared in terms of traditional Chinese medicine syndrome score(cough,wheezing,chest tightness),blood gas indicators[arterial partial pressure of carbon dioxide(PaCO_(2)),arterial partial pressure of oxygen(PaO_(2))],and lung function indicators[forced expiratory volume in one second(FEV1),forced vital capacity(FVC),peak expiratory flow(PEF)]before and after treatment,and clinical efficacy.Results The total effective rate of 93.33%in the observation group was significantly higher than 73.33%in the control group(P<0.05).After treatment,the traditional Chinese medicine syndrome scores in both groups decreased significantly compared with those before treatment;the scores of cough,wheezing and chest tightness were(0.80±0.09),(1.02±0.13)and(0.19±0.15)points in the observation group,which were significantly lower than(1.32±0.14),(2.10±0.22)and(0.70±0.08)points in the control group;the difference was significant(P<0.05).After treatment,the PaO_(2) and PaCO_(2) of the observation group were(80.46±8.12)and(35.28±3.61)mm Hg(1 mm Hg=0.133 kPa),and those of the control group were(69.11±7.01)and(44.86±4.60)mm Hg.Compared with before treatment,PaCO_(2) was significantly decreased and PaO_(2) was significantly increased in both groups after treatment;compared with the control grou

关 键 词：二陈汤 苏子降气汤 穴位埋线 慢性阻塞性肺疾病 痰湿蕴肺型 

分 类 号：R259[医药卫生—中西医结合]