1990~2021年中国归因于高体重指数的成人心血管疾病负担评估  

Assessment of the Burden of Cardiovascular Disease Attributable to High Body Mass Index in Chinese Adults From 1990 to 2021

作　　者：张瑞仙 颜立禧 李真晖 夏爱波[2] ZHANG Ruixian;YAN Lixi;LI Zhenhui;XIA Aibo(Department of Disease Control and Prevention,The First People's Hospital of Yunnan Province,Kunming 650032,China;Medical Department,The First People's Hospital of Yunnan Province,Kunming 650032,China)

机构地区：[1]云南省第一人民医院疾病预防控制科,昆明650032 [2]云南省第一人民医院医务处,昆明650032

出　　处：《中国循环杂志》2024年第12期1211-1216,共6页Chinese Circulation Journal

基　　金：云南省中青年学术和技术带头人及后备人才项目(202405AC350088);云南省应用基础研究/昆医联合专项(202301AY070001-069)。

摘　　要：目的:描述1990~2021年中国归因于高体重指数(BMI)的成人心血管疾病负担变化趋势,明确需控制BMI的重点人群,为实施相关干预策略提供科学依据。方法:基于2021年全球疾病负担(GBD)研究数据库,比较1990~2021年中国与全球及美国、英国、日本、印度四国≥20岁人群归因于高BMI的心血管疾病标化伤残调整生命年(DALY)率与标化死亡率,并按照性别、年龄分层后将中国与全球的相应疾病负担变化趋势进行对比。结果:1990~2021年,中国≥20岁人群归因于高BMI的心血管疾病标化DALY率和标化死亡率均低于美国和全球平均水平,但高于印度和日本,平均年度变化百分比(AAPC)分别为1.08(95%CI:1.05~1.11)和1.00(95%CI:0.96~1.03)。同期,英国的相关心血管疾病负担持续下降,标化DALY率和标化死亡率的AAPC分别为-3.02(95%CI:-3.10~-2.96)和-3.02(95%CI:-3.11~-2.95)。中国成年男性归因于高BMI的心血管疾病标化DALY率持续高于女性,而DALY百分比则相反,女性高于男性。中国≥20岁人群归因于高BMI的心血管疾病标化DALY率持续升高,20~39岁人群归因于高BMI的心血管疾病标化DALY百分比急剧上升,2021年是1990年的3倍以上。结论:中国人群超重和肥胖导致心血管疾病负担持续加重,中青年人群超重的防控对于降低人群心血管疾病负担尤为重要,亟待实施有效的公共卫生干预措施。Objectives:To explore the trend of the burden of cardiovascular disease(CVD)in adult Chinese population attributed to high body mass index(BMI)from 1990 to 2021,identify key populations requiring for BMI control,and provide scientific evidence for developing targeted intervention strategies.Methods:Based on the Global Burden of Disease(GBD)2021 database,we compared the age-standardized disabilityadjusted life years(DALY)rates and age-standardized mortality rates of CVD attributed to high BMI for the adult population aged≥20 years in China,globally,and in the United States,the United Kingdom,Japan,and India from 1990 to 2021.Additionally,the results were stratified by sex and age to compare the trends of disease burden in China and globally.Results:From 1990 to 2021,the average annual percentage change(AAPC)in age-standardized DALY rate and agestandardized mortality rate for CVD attributable to high BMI for the population aged≥20 years in China was 1.08(95%CI:1.05 to 1.11)and 1.00(95%CI:0.96 to 1.03),respectively.Throughout the 32-year period,both rates were consistently lower than those in the United States and the global average,but higher than those in India and Japan.Meanwhile,England experienced a continuous decline,with corresponding data of-3.02(95%CI:-3.10 to-2.96)for AAPC in age-standardized DALY rates and-3.02(95%CI:-3.11 to-2.95)for AAPC in age-standardized mortality rates,respectively.The age-standardized DALY rate attributed to high BMI for adult males in China was consistently higher than those for females,whereas the percentage of DALY showed the opposite trend,with females surpassing males.The age-standardized DALY rates for the population aged≥20 years attributed to high BMI in China increased continuously,and the percentage of DALY increased sharply in population aged 20-39,the level of 2021 was more than three times higher as compared to 1990.Conclusions:The increasing proportion of overweight and obese individuals in China,along with the resulting rise in the prevalence and mortality of c

关 键 词：高体重指数 心血管疾病 伤残调整生命年 疾病负担 

分 类 号：R54[医药卫生—心血管疾病]