芒果苷降尿酸的作用机制及其应用研究进展  

Mechanism for Reducing Uric Acid and Application of Mangiferin

作　　者：赵东 孙宇菲[2] 上官静波 赵锦荣 门靖 ZHAO Dong;SUN Yu-fei;SHANGGUAN Jing-bo;ZHAO Jin-rong;MEN Jing(Engineering Research Center of Personalized Anti-aging Health Product Development and Transformation,Universities of Shaanxi Province,Xi'an 710077,China;College of Medicine,Xi'an International University,Xi'an 710077,China;Xi'an Wanlong Pharmaceutical Co.,Ltd.,Xi'an 710119,China)

机构地区：[1]精准抗衰健康产品研发与转化陕西省高校工程研究中心,陕西西安710077 [2]西安外事学院医学院,陕西西安710077 [3]西安万隆制药股份有限公司,陕西西安710119

出　　处：《精细化工中间体》2024年第6期1-6,共6页Fine Chemical Intermediates

基　　金：陕西省教育厅科学研究计划项目(No.23JK0627);陕西省重点研发计划项目(No.2022SF-570);陕西省高层次人才启动基金项目(No.XAIU202005)。

摘　　要：芒果苷是芒果叶中主要的黄酮类化学成分,具有高效的抗高尿酸血症药理作用。芒果苷可通过抑制尿酸生成和促进尿酸排泄途径,调节体内尿酸平衡,改善肾功能异常。综述了近年来芒果苷降尿酸作用机制及其应用研究进展,并对芒果叶药用资源的开发利用、天然成分芒果苷的研究方向进行了展望。Mangiferin,a chemical compound found in mango leaves,is found to have an effective pharmacological effect in treating hyperuricemia.Research indicates that mangiferin can inhibit uric acid production and increase its excretion,thus improving kidney function and maintaining uric acid balance.The paper systematically reviews the mechanisms by which mangiferin reduces uric acid levels.Additionally,it discusses the potential for utilizing mango tree leaves as medicinal resource and puts forward the study trends of the natural ingredient mangiferin which extracts primarily from mango tree leaves.

关 键 词：芒果苷 芒果叶 尿酸 高尿酸血症 研究进展 

分 类 号：R285.5[医药卫生—中药学] TQ461[医药卫生—中医学]