内镜下硬化剂注射治疗Ⅰ~Ⅲ度内痔的临床疗效分析  

Clinical Efficacy of Endoscopic Injection Sclerotherapy for GradeⅠtoⅢInternal Hemorrhoids

作　　者：杨智 仝巧云[1] Yang Zhi;Tong Qiaoyun(Department of Gastroenterology,Yichang Central People's Hospital,The First College of Clinical Medical Science,China Three Gorges University&The Institute of Digestive Diseases,China Three Gorges University,Yichang 443003,China)

机构地区：[1]三峡大学第一临床医学院[宜昌市中心人民医院]消化内科&三峡大学消化疾病研究所,湖北宜昌443003

出　　处：《巴楚医学》2024年第4期83-87,共5页Bachu Medical Journal

基　　金：国家自然科学基金项目(No:82100566)。

摘　　要：目的:探讨内镜下硬化剂注射疗法(EIS)在Ⅰ~Ⅲ度内痔患者中的治疗效果。方法:选取2023年2月—2024年4月在宜昌市中心人民医院就诊的Ⅰ~Ⅲ度内痔100例患者,其中接受ESI的为观察组(n=43),接受吻合器痔上黏膜环切术(PPH)的为对照组(n=57),比较两组患者的临床疗效。结果:两组患者治疗有效率无明显差异;与对照组相比,观察组患者手术时间[(16.53±4.61)min vs(29.65±7.84)min]、术中失血量[(7.14±2.32)mL vs(18.62±4.22)mL]、止痛次数[(4.15±1.35)次vs(9.87±2.37)次]、住院时间[(5.45±1.14)天vs(7.64±1.52)天]及住院费用[(4.13±1.12)千元vs(6.63±1.24)千元]均明显减少,观察组患者术后24小时及术后30天疼痛程度明显减轻(均P<0.05);观察组患者并发症发生率(9.30%vs 45.61%)明显低于对照组(P<0.05)。结论:EIS和PPH治疗Ⅰ~Ⅲ度内痔患者的治疗有效率无明显差异,接受EIS的患者手术时间短、术中出血量少、术后疼痛程度较轻、并发症发生率低且住院费用低。Objective:To investigate the therapeutic effect of endoscopic injection sclerotherapy(EIS)in patients with gradeⅠ~Ⅲinternal hemorrhoids.Methods:A total of 100 patients with gradeⅠ~Ⅲinternal hemorrhoids who were treated in Yichang Central People's Hospital from February 2023 to April 2024 were selected.Among them,patients who received EIS were assigned to the observation group(n=43),and those who received procedure for prolapsing and hemorrhoids(PPH)were assigned to the control group(n=57).The clinical efficacy of the two groups was compared.Results:There was no significant difference in the treatment efficiency between the two groups.Compared with the control group,the operation time[(16.53±4.61)min vs(29.65±7.84)min],intraoperative blood loss[(7.14±2.32)mL vs(18.62±4.22)mL],number of analgesic administrations[(4.15±1.35)times vs(9.87±2.37)times],hospital stay[(5.45±1.14)days vs(7.64±1.52)days],and hospitalization expenses[(4.13±1.12)thousand yuan vs(6.63±1.24)thousand yuan]were significantly reduced in the observation group,and the pain intensity at 24 hours and 30 days after surgery was significantly lower in the observation group(all P<0.05).The incidence of complications in the observation group(9.30%vs 45.61%)was significantly lower than that in the control group(P<0.05).Conclusion:There was no significant difference in the treatment efficiency between EIS and PPH in patients with gradeⅠ~Ⅲinternal hemorrhoids.Patients receiving EIS had shorter operation time,less intraoperative blood loss,milder postoperative pain,lower incidence of complications,and lower hospitalization expenses.

关 键 词：内镜下硬化剂注射疗法 吻合器痔上黏膜环切术 内痔 

分 类 号：R657.18[医药卫生—外科学]