复方黄柏液涂剂湿敷联合红蓝光照射对青少年寻常痤疮患者皮肤生理指标及皮损状态修复的影响  

Effects of wet application of compound Phellodendri liquid coating combined with red and blue light irradiation on skin physiological indexes and skin lesion repair in adolescent patients with acne vulgaris

作　　者：张译丹 王芳[1] 王廷廷 王胜春 Zhang Yi-dan;Wang Fang;Wang Ting-ting;Wang Sheng-chun(Department of Dermatology,Children's Hospital Affiliated to Zhengzhou University,Henan Children's Hospital,Zhengzhou 450000,China)

机构地区：[1]郑州大学附属儿童医院·河南省儿童医院郑州儿童医院皮肤科,河南郑州450000

出　　处：《四川生理科学杂志》2024年第12期2639-2641,2817,共4页

摘　　要：目的:探究复方黄柏液涂剂湿敷联合红蓝光照射对青少年寻常痤疮患者皮肤生理指标及皮损状态修复的影响。方法:选取我科2021年11月至2023年11月期间97例青少年寻常痤疮患者作为研究对象,对照组48例单纯红蓝光照射,观察组49例复方黄柏液涂剂湿敷联合红蓝光照射,对比两组患者临床疗效、皮肤生理指标、皮损状态及不良反应。结果:治疗2个疗程后,观察组有效率明显高于对照组(P<0.05)。两组皮肤生理指标评分均降低(P<0.05),且观察组更低(P<0.05)。治疗2个疗程后,两组患者的皮损状态评分均下降(P<0.05),且观察组更低(P<0.05)。两组不良反应发生率无明显差异(P>0.05)。结论:复方黄柏液涂剂湿敷联合红蓝光照射能够提高青少年寻常痤疮患者的临床疗效,改善皮肤生理指标并修复皮损状态。Objective:To explore the effects of wet application of compound Huangbai-liquid coating combined with red and blue light irradiation on skin physiological indexes and skin lesion repair in adolescent patients with acne vulgaris.Methods:Ninety-seven cases of adolescent acne vulgaris patients in our department from November 2021 to November 2023 were selected as research objects,forty-eight cases in the control group were exposed to red and blue light alone,and forty-nine cases in the observation group were wet compress combined with red and blue light.Clinical efficacy,skin physiological indexes,skin lesions and adverse reactions were compared between the two groups.Results:After two courses of treatment,the effective rate of observation group was significantly higher than that of control group(P<0.05).The scores of skin physiological indexes in both groups were decreased(P<0.05),and those in the observation group were lower(P<0.05).After two courses of treatment,the score of lesion status of both groups decreased(P<0.05),and the score of observation group was lower(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Wet compress combined with red and blue light irradiation can improve the clinical efficacy of adolescent acne vulgaris patients,improve skin physiological indexes and repair skin lesions.

关 键 词：复方黄柏液涂剂 红蓝光 寻常痤疮 皮肤生理指标 皮损状态 

分 类 号：R758.733[医药卫生—皮肤病学与性病学]