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作 者:李亚亚 张文兰 胡永鹏 李秋林 罗维芸 Li Yaya;Zhang Wenlan;Hu Yongpeng;Li Qiulin;Luo Weiyun(The Second People s Hospital of Gansu Province,Lanzhou 730030,China)
出 处:《亚太传统医药》2025年第1期54-57,共4页Asia-Pacific Traditional Medicine
摘 要:目的:探讨在督脉筋经理论指导下,应用督脉刺骨术治疗中轴型强直性脊柱炎的临床效果。方法:选取2023年3月-2024年3月,经半年以上常规治疗效果不明显的中轴型活动期强直性脊柱炎患者50例作为研究对象。采用随机对照试验法,将研究对象分为对照组和观察组,每组各25例。对照组主要给予依那西普注射液控制病情,观察组在此基础上联合督脉刺骨术治疗。治疗1个月后,比较两组患者治疗前后BASFI(强直性脊柱炎功能指数)评分、BathBASDAI(Bath强直性脊柱炎疾病活动度)评分、VAS(脊柱疼痛)评分、关节活动度情况(枕墙距、指地距、Schober试验、晨僵时间)及红细胞沉降率(ESR)、C反应蛋白(CRP)水平。结果:经治疗后,观察组BASFI评分、BASDAI评分、VAS评分、关节活动度及ESR、CRP水平改善明显,与对照组相比差异有统计学意义(P<0.05)。结论:生物制剂依那西普注射液配合督脉刺骨术治疗中轴型强直性脊柱炎疗效更加显著,能有效减轻患者病痛,改善脊柱功能,并且副作用小,安全性好。Objective:To explore the clinical effect of using Du Meridian bone piercing surgery to treat axial ankylosing spondylitis under the guidance of Du Meridian Tendon Meridian theory.Methods:Fifty patients with axial active ankylosing spondylitis who have not shown significant results in conventional treatment for more than six months from March 2023 to March 2024 were selected as the study subjects.Using a randomized controlled trial method,the study subjects were divided into a control group and an observation group,with 25 cases in each group.The control group was mainly given etanercept injection to control the condition,while the observation group received combined treatment with Du Meridian bone piercing surgery on this basis.After one month of treatment,the BASFI(Ankylosing Spondylitis Functional Index)score,BathBASDAI(Bath Ankylosing Spondylitis Disease Activity)score,VAS(Spinal Pain)score,joint activity(occipital wall distance,finger to ground distance,Sch ber test,morning stiffness time),erythrocyte sedimentation rate(ESR),and C-reactive protein(CRP)levels were compared between the two groups of patients before and after treatment.Results:After treatment,the observation group showed significant improvements in BASFI score,BASDAI score,VAS score,joint range of motion,ESR,and CRP levels,with statistical significance(P<0.05)compared to the control group.Conclusion:The combination of biological agent etanercept injection and Du Meridian bone piercing surgery has a more significant therapeutic effect on axial ankylosing spondylitis,which can effectively alleviate patients pain,improve spinal function,and have fewer side effects and good safety.
分 类 号:R274[医药卫生—中医骨伤科学]
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