藤类中药抗风湿用药规律研究  

Study on the Law of Anti-Rheumatic Medicines of Rattan-Derived Medicinal Materials

作　　者：杨媛媛 王苑桃 王新晓 胡静 鲁文静[1] 陈志永 Yang Yuanyuan;Wang Yuantao;Wang Xinxiao;Hu Jing;Lu Wenjing;Chen Zhiyong(Shaanxi Academy of Traditional Chinese Medicine,Xi an 710061,China;Xi an Institute for Food and Drug Control,Xi an 710054,China;Xi an Fifth Hospital,Xi an 710082,China)

机构地区：[1]陕西省中医药研究院,陕西西安710061 [2]西安市食品药品检验所,陕西西安710054 [3]西安市第五医院,陕西西安710082

出　　处：《亚太传统医药》2025年第1期142-148,共7页Asia-Pacific Traditional Medicine

基　　金：国家自然科学基金面上项目(81973419);陕西省重点研发计划一般项目(2022SF-315);陕西省中医药管理局“双链融合”中青年科研创新团队(2022-SLRH-YQ-003);陕西省中医药管理局省级专项资金项目(SZY-KJCYC-2023-057);西安市科技计划项目(22YXYJ0113)。

摘　　要：目的:分析总结藤类中药抗风湿用药规律。方法:梳理含藤类药材的抗风湿中成药,结合关联规则分析,挖掘用药规律;通过文献检索,综述常用藤类中药化学成分、抗风湿机制等。结果:筛选出包含藤类药材的抗风湿中成药82种,涉及藤类药材37种。常用藤类药材主要分为温通散寒类、祛风止痛类、清热通络类、祛瘀活血类、养血通络类,应根据风湿病程选择药物。藤类药物常配伍使用,如鸡血藤-海风藤、青风藤-海风藤、海风藤-络石藤等。海风藤、宽筋藤、石南藤等抗风湿药效物质、疗效机制等尚需深入研究。结论:该研究可为藤类药材抗风湿领域应用,以及中药制剂、创新中药的研发提供参考。Objective:To analyze and summarize rattan-derived anti-rheumatic medicinal materials compatibility rules.Methods:The anti-rheumatic Chinese patent medicines containing rattan were sorted out and the rules of drug use were mined by association rule analysis.The chemical constituents and anti-rheumatic mechanism of rattan-derived medicinal materials were reviewed by literature search.Results:82 kinds of anti-rheumatism Chinese patent medicines containing rattan were screened out,with 37 kinds of rattan involved.Commonly used rattan herbs can be categorized as warming and relieving cold,dispelling wind,and relieving pain,clearing heat and dredging collaterals,removing blood stasis and promoting blood circulation,nourishing blood,and unblocking collaterals.Drugs should be selected according to the illness duration of rheumatism.Rattan herbs are often used in pairs,such as Spatholobi Caulis-Piperis Kadsurae Caulis,Sinomenii Caulis-Piperis Kadsurae Caulis,Piperis Kadsurae Caulis-Trachelospermi Caulis et Folium,etc.The anti-rheumatic substances and therapeutic mechanism of Piperis Kadsurae Caulis,Tinospora sinensis,and Piper wallichii must be further studied.Conclusion:This study will provide ideas and a basis for applying rattan-derived medicinal materials in the field of anti-rheumatism,as well as the research and development of traditional Chinese medicine preparations and innovative traditional Chinese medicine in medical institutions.

关 键 词：藤类中药 抗风湿 用药规律 化学成分 作用机制 

分 类 号：R28[医药卫生—中药学] R255.6[医药卫生—中医学]