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作 者:仁真多吉 才让南加 占堆 Renzhen Duoji;Cairang Nanjia;Zhan Dui(Tibet Tibetan Medical University,Lhasa 850000,China)
出 处:《亚太传统医药》2025年第1期156-160,共5页Asia-Pacific Traditional Medicine
基 金:西藏藏医药大学中药学博士点培育项目(BSTD-202302)。
摘 要:目的:基于数据挖掘探析藏药材天门冬的用药规律及应用特点。方法:以《藏药方剂大全》和《藏医药经典文献集成》为数据来源建立含天门冬方剂数据库,利用Excel 2021办公软件、IBM SPSS Modeler 18.0、IBM SPSS Statistics 23.0等对纳入方剂进行分析。结果:最终纳入89首含天门冬的方剂,共涉及274味藏药,累计使用1352次,且与之同时出现的高频次单味药材(≥15)有黄精(78)、蒺藜(57)、喜马拉雅紫茉莉(56)等25种。对高频单味药材(≥20)进行性味和功效分析得出药味中甘味占比最大,药性以温性为主,功效以健胃和补肾为主,主治疾病以肾脏寒病、妇科病、黄水病为主。关联规则分析显示,药对组合中天门冬-黄精,天门冬-蒺藜的支持度较高,三味药组中天门冬-黄精-喜马拉雅紫茉莉的支持度最高。治疗肾脏寒病时,藏药五大根为常出现的组合药,聚类分析得到5类治疗肾脏寒病的基本药物组合。结论:天门冬主要出现于治疗肾脏寒病的方剂中,且其配伍规律遵循藏医药“三胃火”平衡的基本理论及辨证论治原则。Objective:To explore the medication rules and application characteristics of prescription containing asparagus officinalis based on data mining.Methods:A database of Asparagus officinalis formula was established with Tibetan medicine formula Daquan and Tibetan medicine classic literature integration as data sources,and the included formulas were analyzed by Excel 2021 office software,IBM SPSS Modeler 18.0,IBM SPSS Statistics 23.0,etc.Results:Eighty-nine prescriptions containing Asparagus officinalis were finally included,involving a total of 274 Tibetan medicines,which were used a total of 1352 times cumulatively,and 25 high-frequency single herbs(≥15)that appeared at the same time were Polygonatum cirrhifolium(78),Tribulus terrestris(57),Himalayan purple jasmine(56),and so on.Analysis of the taste effect of high frequency single herbs(≥20)showed that sweet taste accounted for the largest proportion of herbs,the medicinal properties were mainly warm,and the efficacy was mainly stomach strengthening and kidney tonifying.Attending diseases were mainly kidney cold disease,gynecological disease,yellow water disease.Association rule analysis showed that the support degree of Asparagus-Polygonatum cirrhifoliu and Tribulus terrestris was higher in the drug pair combination,and Asparagus-Polygonatum cirrhifolium-Himalayan purple jasmine was the highest in the three herb groups.In the treatment of kidney cold disease,the five roots of Tibetan medicine were commonly occurring combinations,and cluster analysis found five basic drug combinations for the treatment of kidney cold disease.Conclusion:Asparagus officinalis mainly appears in the prescription of treating kidney cold disease,and its compatibility rules follow the basic theory of Tibetan medicine“three stomach fire”balance and the principle of syndrome differentiation and treatment.
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