基于“膜腠三焦”理论分期论治特发性肺纤维化  

Staging Treatment of Idiopathic Pulmonary Fibrosis Based on "Membrane-Interstice-Three jiao" Theory

作　　者：吴宣諭 肖祥 杜全宇 王飞[1] 杨晗[1] WU Xuanyu;XIAO Xiang;DU Quanyu;WANG Fei;YANG Han(Hospital of Chengdu University of TCM,Chengdu Sichuan 610072,China)

机构地区：[1]成都中医药大学附属医院,四川成都610072

出　　处：《中医药导报》2024年第12期107-110,共4页Guiding Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家自然科学基金面上项目(82174347,82374403);四川省中医药管理局中医药科研专项课题面上项目(2023MS363)。

摘　　要：“膜腠三焦”理论由成都中医药大学陈潮祖提出,其认为三焦是由膜与腠构成,是气血精津液运行的通道,影响全身物质代谢与能量流通。特发性肺纤维化病理演进与“肺痹-肺痿”病程转归特点高度契合,膜腠失和,三焦失司贯穿其病程始终:炎症期久病肺虚,复感外邪,膜腠不利;纤维化形成期痰瘀蕴毒,痹阻不行,膜腠僵硬;纤维化期膜损腠衰,三焦枯槁,痿废失用。强调调理膜腠、疏利三焦的基本治则,分期采用“疏、消、养”三大治法:一者祛邪利肺,疏达膜腠;二者消癥除积,解痉和络;三者敛肌止损,资生化源。将中医病机与现代病理相结合,丰富中医药辨治本病理论内涵。The theory of "membrane-interstice-three jiao" was put forward by Professor CHEN Chaozu of Chengdu University of TCM.He believed that the three jiao consists of the membrane and the interstice,and it is a channel for the operation of qi,blood,essence,and body fluid,which affects the metabolism and energy flow of the whole body.The pathological evolution of idiopathic pulmonary fibrosis(IPF) and "lung paralysis-lung wither" disease process transition characteristics are highly compatible.We believe that the membrane-interstice disharmony and the three jiao imbalance are throughout the IPF.During the inflammatory period,chronic diseases can develop into lung deficiency,making the patient more susceptible to other pathogenic qi,resulting in membrane-interstice discomfort.During fibrosis formation,phlegm,blood stasis,and toxin block the membraneinterstice,causing its stiffness.During the fibrosis period,the membrane-interstice is damaged,and the three jiao withers until it fails to function normally.This article emphasizes regulating the membrane-interstice,dredging the three jiao of the basic principles,phased use of "dredge,eliminating,tonifying" three primary treatments:firstly,to eliminate the evil qi in lungs,and dredge the membrane-interstice;secondly,to eliminate the product of excess,and reduce the spasms;thirdly,to promote wound recovery,and nourish the body.The combination of TCM pathogenesis and modern pathology enriches the theoretical connotation of TCM in treating IPF.

关 键 词：特发性肺纤维化 膜腠三焦 分期论治 肺痹 肺痿 

分 类 号：R256.15[医药卫生—中医内科学]