Long-Term Exposure to Low-Level Ambient Air Pollution and Mortality among 0.3 Million Chinese Older Adults  

作　　者：Likun Liu Xueli Yuan Wenqing Ni Jing Wei Tingting Liu Ruijun Xu Yingxin Li Zihua Zhong Yi Zheng Sihan Liang Rui Wang Jian Xu Yuewei Liu 

机构地区：[1]Department of Epidemiology,School of Public Health,Sun Yat-sen University,Guangzhou 510080,Guangdong,China [2]Department of Elderly Health Management,Shenzhen Center for Chronic Disease Control,Shenzhen 518020,Guangdong,China [3]Department of Atmospheric and Oceanic Science,Earth System Science Interdisciplinary Center,University of Maryland,College Park,MD 20740,USA [4]Shenzhen Maternity&Child Healthcare Hospital,Shenzhen 518017,Guangdong,China [5]LuoHu District Chronic Disease Hospital,Shenzhen 518024,Guangdong,China

出　　处：《Biomedical and Environmental Sciences》2024年第12期1362-1372,共11页生物医学与环境科学（英文版）

基　　金：supported by the National Natural Science Foundation of China(grant no.82273631);the Science and Technology Planning Project of Shenzhen City,Guangdong Province,China(grant no.JCYJ20220531094410024);the Shenzhen Medical Key Discipline Construction Fund,Guangdong Province,China(grant no.SZXK065).

摘　　要：Objective Evidence that long-term exposure to ambient air pollution increases mortality among older adults,particularly those residing in low-level air pollution locations,remains scarce.This study investigated the potential links between long-term low-level air pollution exposure and mortality among Chinese older adults.Methods A population-based study with 317,464 individuals aged≥65 years was conducted in Shenzhen,China during 2018 and 2020.Logistic regression models were used to analyze the associations between long-term exposure to air pollution and all-cause mortality,as the primary outcome,as well as non-accidental,cancer and cardiovascular mortality.Results Significant associations of PM1,PM_(2.5),PM_(10),SO_(2),CO,and O3 exposures with a higher risk of all-cause mortality were found.Adjusted odds ratio(OR)for each 1μg/m^(3) increment was 1.49[95%confidence interval(CI):1.46,1.53]for PM1,1.30(1.27,1.32)for PM_(2.5),1.05(1.04,1.06)for PM_(10),5.84(5.39,6.32)for SO_(2),1.04(1.04,1.05)for CO,and 1.02(1.00,1.03)for O3,respectively.Long-term PM1,PM_(2.5),PM_(10),SO_(2),and CO exposures also elevated the risks of non-accidental,cancer and cardiovascular mortality.Conclusion Long-term low-level air pollution exposure was associated with an increased mortality risk among Chinese older adults.

关 键 词：Ambient air pollution MORTALITY Older adults Population-based study Low-level concentrations 

分 类 号：R195.4[医药卫生—卫生统计学]