Glyphosate Based-Herbicide Induced Nephrotoxicity through Oxidative Stress and the Imbalance of Osmotic Pressure in Mice  

作　　者：Lei Qi Jinfeng Zhu Yanbo Qi Hong Chao Yu Cheng Xiaolei Yang Hongjie Li Gang Li Jicheng Liu 

机构地区：[1]School of Public Health,Qiqihar Medical University,Qiqihar 161006,Heilongjiang,China [2]Qiqihar Academy of Medical Sciences,Qiqihar 161006,Heilongjiang,China [3]Postdoctoral Research Station of Qiqihar Institute of Medical Science,Qiqihar 161006,Heilongjiang,China

出　　处：《Biomedical and Environmental Sciences》2024年第12期1453-1457,共5页生物医学与环境科学（英文版）

基　　金：supported by the Fundamental Research Funds for the Department of Education in Heilongjiang Province(Grant No.2020-KYYWF-0037 and No.2019-KYYWF-1277);National Natural Science Foundation of China(No.82103869);Project of Qiqihar Academy of Medical Sciences(Grant No.QMSI2019M-23,No.QMSI2019M-05 and No.2024-ZDPY-003);Technology Plan Joint Guidance Project of Qiqihar(Grant No.LHYD-202007);Doctor Youth Fund of Qiqihar Academy of Medical Sciences(Grant No.QMSI2023B-13);Technology Plan Joint Guidance Project of Qiqihar(Grant No.LSFGG-2024100).

摘　　要：Glyphosate-based herbicides(GBHs)are used for weeding purposes in orchards and rubber plantations,as well as in the cultivation of tea mulberry and genetically modified crops.In recent years,GBH has become the most widely used organic phosphorus pesticide.Glyphosate and its metabolites can easily chelate metals,resulting in the formation of persistent residues that are frequently detected in natural environments.Recently,an increasing number of past studies have indicated that glyphosate exposure may be a risk factor for mental disease,liver,and tumorigenesis[1,2].Therefore,the widespread use of GBHs poses potential public health risks.

关 键 词：rubber CHELATE RESIDUES 

分 类 号：R994.3[医药卫生—毒理学]