环泊酚在双向接头型伸缩管连接喉罩无痛支气管镜检查治疗中的应用  

Application of cyclopofol in painless bronchoscopy using bidirectional telescopic tube connected laryngeal mask

作　　者：康欢 刘晓玮 刘文雄 Kang Huan;Liu Xiao-wei;Liu Wen-xiong(Department of Anesthesiology,Xidian Group Hospital,Xi’an 710077,China)

机构地区：[1]西电集团医院麻醉科,西安710077

出　　处：《中国药物应用与监测》2024年第6期760-763,共4页Chinese Journal of Drug Application and Monitoring

基　　金：通用环球医疗集团有限公司科研扶持基金项目(UM0122002)。

摘　　要：目的探讨环泊酚在双向接头型伸缩管连接喉罩无痛支气管镜检查治疗中的麻醉效果。方法选取西电集团医院麻醉科2023年1月至2023年12月入院行双向接头型伸缩管连接喉罩无痛支气管镜检查或治疗的115例受检者,按使用麻醉药物的不同分为研究组63例和对照组52例,研究组给予环泊酚、对照组给予丙泊酚诱导麻醉及维持麻醉。比较两组血流动力学、麻醉时间相关指标、不良反应发生情况。结果研究组和对照组平均脉动压(MAP)在进镜前为(92.55±15.43)mm Hg(1 mm Hg≈0.133 kPa)、(86.55±13.31)mm Hg,均低于麻醉前[(98.15±14.22)mm Hg、(98.55±14.32)mm Hg],差异均有统计学意义(t=2.118,4.426,均P<0.05),且进镜前研究组MAP高于对照组,差异有统计学意义(t=2.207,P<0.05);检查中研究组MAP[(99.44±11.37)mm Hg]高于对照组[(95.37±8.33)mm Hg],差异有统计学意义(t=2.148,P<0.05);研究组术前注射痛、术中呼吸抑制发生率分别为17.46%(11/63)、22.22%(14/63),对照组分别为44.23%(23/52)、46.15%(24/52),两组比较差异有统计学意义(χ^(2)=9.804,7.374,均P<0.05);研究组镜检时间、受检者苏醒时间及定向力恢复时间依次为(21.55±2.38)min、(10.49±2.57)min、(17.37±2.45)min,均短于对照组[(23.47±3.46)min、(12.55±2.56)min、(18.92±2.16)min],差异均有统计学意义(t=3.513,4.286,3.560,均P<0.05)。结论环泊酚在双向接头型伸缩管连接喉罩无痛支气管镜检查治疗中有助于稳定血流动力学,缩短镜检时间并减少不良反应的发生,麻醉效果较好。Objective To investigate the anesthetic effect of cypofol in painless bronchoscopy using bidirectional telescopic tube connected laryngeal mask.Methods A total of 115 patients admitted to Xidian Group Hospital from January 2023 to December 2023 for painless bronchoscopy using bidirectional tractable tube connected laryngeal hood were retrospectively selected as the research subjects.According to the use of different anesthesia drugs,they were divided into the study group(n=63)and control group(n=52).The patients in the study group were given cypofol while those in the control were given propofol to induce and maintain anesthesia.The hemodynamics,time indexes and the occurrence of adverse reactions were compared between the two groups.Results The mean pulse pressure(MAP)of the study group and the control group was(92.55±15.43)mm Hg and(86.55±13.31)mm Hg(1 mm Hg≈0.133 kPa).They were lower than those before anesthesia((98.15±14.22)mm Hg and(98.55±14.32)mm Hg),the difference was statistically significant(t=2.118,4.426,both P<0.05).The MAP of the study group was higher than that of the control before surgery,the difference was statistically significant(t=2.207,P<0.05).During the surgery,the MAP was(99.44±11.37)mm Hg in the study group,which was higher than that of(95.37±8.33)mm Hg in the control group,showing statistically significant difference(t=2.148,P<0.05).The incidence of injection pain before surgery and respiratory depression during surgery were 17.46%(11/63)and 22.22%(14/63)in the study group,and 44.23%(23/52)and 46.15%(24/52)in the control group,respectively,and there was significant difference between the two groups(χ^(2)=9.804,7.374,both P<0.05).The microscopic examination time,recovery time and orientation recovery time of the study group were(21.55±2.38)min,(10.49±2.57)min,(17.37±2.45)min,respectively.They were shorter than those in the control group((23.47±3.46)min,(12.55±2.56)min and(18.92±2.16)min),demonstrating statistical significance(t=3.513,4.286,3.560,all P<0.05).Conclusion Cypofol

关 键 词：环泊酚 双向接头型伸缩管 支气管镜检查治疗 无痛 喉罩 

分 类 号：R614[医药卫生—麻醉学]