穴位埋线联合丹莪妇康煎膏治疗子宫内膜异位症痛经疗效及对患者血清CA125的影响  

Clinical efficacy and effect on serum CA125 of acupoint catgut embedding combined with Dan’e Fukang decoction in the treatment of endometriosis dysmenorrhea

作　　者：刘玲慧 袁滢 潘玉 张婕[1] 丁天增 张天婵[2] LIU Linghui;YUAN Ying;PAN Yu;ZHANG Jie;DING Tianzeng;ZHANG Tianchan(Heilongjiang University of Chinese Medicine,Harbin 150040,China)

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150040 [2]黑龙江中医药大学附属第二医院,黑龙江哈尔滨150001

出　　处：《陕西中医》2025年第1期122-125,共4页Shaanxi Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(81704113);黑龙江中医药大学研究生创新科研项目(2024YJSCX034)。

摘　　要：目的:探究采用穴位埋线联合丹莪妇康煎膏疗法对子宫内膜异位症(EMs)痛经患者(气滞血瘀型)的临床治疗效果及其对血清糖类抗原125(CA125)的影响。方法:将66例EMs痛经患者(气滞血瘀型)随机分为两组,各33例。对照组给予丹莪妇康煎膏治疗,观察组在此基础上辅以穴位埋线疗法,两组均连续治疗3个月经周期。记录两组患者的临床疗效和不良反应;比较治疗前、治疗3个月经周期后经期视觉模拟评分量表(VAS)评分、痛经症状评分、气滞血瘀型痛经的中医证候积分及血清CA125水平变化。结果:观察组总有效率96.77%高于对照组86.67%(P<0.05);治疗3个月经周期后,两组的经期VAS评分、痛经症状评分、气滞血瘀型痛经中医证候积分及血清CA125水平均较治疗前降低,且在上述指标的改善幅度方面,观察组均显著优于对照组(均P<0.05);两组不良反应率比较差异无统计学意义(P>0.05)。结论:穴位埋线联合丹莪妇康煎膏可有效缓解气滞血瘀型EMs痛经及其伴随症状,改善中医证候,且能降低血清CA125水平、抑制异位内膜进展,提高临床疗效。Objective:To observe the clinical efficacy and effect on serum carbohydrate antigen 125(CA125)of acupoint catgut combined with Dan’e Fukang decoction in the treatment of dysmenorrhoea in endometriosis(EMs)of the qi stagnation and blood stasis type.Methods:66 patients were randomly divided into two groups of 33 each with dysmenorrhea in qi stagnation and blood stasis EMs.The control group was treated orally with Dan’e Fukang decoction,and the observation group was supplemented with acupoint catgut on this basis,and both groups were treated for 3 consecutive menstrual cycles.The clinical efficacy of the two groups was compared.The visual analogue scale(VAS)scores,dysmenorrhoea scores,Chinese medicine symptom scores and serum CA125 levels were compared before and after the treatment,and the adverse reactions during the treatment period were observed and recorded.Results:Follwing treatment,treatment efficacy was higher in the observed group than those in the control group(P<0.05).The menstrual VAS score,dysmenorrhoea symptom score,Chinese medicine symptom score and serum CA125 level of the patients in both groups were reduced compared with the pre-treatment period,and the increase in attractiveness indices of the observation group was better than those in the control group(all P<0.05).Side effect rates had no statistically significant(P>0.05).Conclusion:Acupoint catgut embedding combined with Dan’e Fukang decoction can effectively relieve dysmenorrhoea and its accompanying symptoms in EMs with qi stagnation and blood stasis,improve the Chinese medicine evidence,and can reduce serum CA125 level,inhibit the progress of ectopic endothelium,and improve the clinical efficacy.

关 键 词：子宫内膜异位症 痛经 穴位埋线 丹莪妇康煎膏 气滞血瘀型 血清糖类抗原125 

分 类 号：R711.71[医药卫生—妇产科学]