石斛属类植物化学成分提取分离精制的研究进展  

Research progress on the extraction,separation,and purification of chemical constituents from Dendrobium species

作　　者：韩硕 李成网[2] 刘增辉[2] 宫鹏[3] Han Shuo;Li Chengwang;Liu Zenghui;Gong Peng(Joint Cultivation Department,College of Pharmacy,Anhui Medical University,Anhui 230031,Hefei Province,China;Medicine and Health Inspection and Testing Center,Anhui Academy of Medical Sciences,Anhui 230061,Hefei Province,China;Third-Level Chemistry Laboratory of Traditional Chinese Medicine,State Administration of Traditional Chinese Medicine,Department of Pharmacy,The First Affiliated Hospital of Anhui Medical University,Hefei230022,Anhui Province,China)

机构地区：[1]安徽医科大学药学院联合培养教研室,合肥230031 [2]安徽省医学科学研究院医药卫生检验检测中心,合肥230061 [3]国家中医药管理局中药化学三级实验室,安徽医科大学第一附属医院药剂科,合肥230022

出　　处：《中国基层医药》2024年第12期1915-1920,共6页Chinese Journal of Primary Medicine and Pharmacy

基　　金：安徽省卫生健康委科研计划(AHWJ2021a018);2022年度高等学校省级质量工程项目(2022kcsz149);安徽省高校自然科学基金重点项目(2024AH050851)。

摘　　要：石斛素有“药中黄金”之称,历代医家视为中药之极品,多以茎入药,其含有多糖、生物碱、黄酮、联苄类、菲类、酚类、苯丙素、烯类、植物甾醇、氨基酸及微量元素和挥发油等。石斛的叶和花也含有多种化学成分,但其叶和花化学成分的分离和精制方法还不完善,严重影响了石斛深度全效利用开发。该研究查阅了近年来石斛属植物研究的大量文献,根据石斛茎、花及叶的特点,探讨了其有效成分和提取分离精制方法,为未来石斛属植物的综合利用开发及石斛属产业的可持续发展提供有力技术支撑。Dendrobium has long been referred to as the"gold in medicine"and is highly valued as a key component of traditional Chinese medicine.It is primarily the stems of Dendrobium that are used,containing a variety of compounds such as polysaccharides,alkaloids,flavonoids,bibenzyl analogs,phenolics,phenylpropanoids,alkenes,phytosterols,amino acids,trace elements,and volatile oils.Although the leaves and flowers of Dendrobium also contain numerous chemical constituents,the methods for separating and purifying these components are still not fully developed.This limitation has hindered the comprehensive utilization and development of Dendrobium.This review analyzes a substantial body of recent literature on Dendrobium species and explores their effective components,as well as the methods for extraction,separation,and purification of the stems,flowers,and leaves.Findings from this review help provide essential technical support for the comprehensive utilization of Dendrobium species and the future development of the Dendrobium industry.

关 键 词：中草药 石斛属 花 叶子 植物提取物 化学技术 分析 综述 

分 类 号：R284.2[医药卫生—中药学]