注射用糜蛋白酶联合鼻负压置换治疗慢性鼻窦炎的临床效果  

Clinical Effect of Chymotrypsin for Injection Combined with Nasal Negative Pressure Replacement in the Treatment of Chronic Sinusitis

作　　者：雷关民 陈春霞[1] 朱俊茹 LEI Guanmin;CHEN Chunxia;ZHU Junru(Department of Otorhinolaryngology,Anyang Second People's Hospital,Anyang 45500,China;Department of Otorhinolaryngology,A nyang Maternal and Child Health Hospital,A nyang 455000,China)

机构地区：[1]安阳市第二人民医院耳鼻咽喉科,河南安阳455000 [2]安阳市妇幼保健院耳鼻咽喉科,河南安阳455000

出　　处：《临床医学工程》2024年第12期1473-1474,共2页Clinical Medicine & Engineering

摘　　要：目的探讨注射用糜蛋白酶联合鼻负压置换治疗慢性鼻窦炎的效果。方法60例慢性鼻窦炎患者随机分为两组。对照组采用鼻负压置换治疗,研究组采用注射用糜蛋白酶联合鼻负压置换治疗。比较两组的治疗效果。结果治疗后,研究组的总有效率、MCC、MTR均高于对照组,Lund-Kennedy评分、Lund-Mackey评分均低于对照组(P<0.05)。结论注射用糜蛋白酶联合鼻负压置换治疗慢性鼻窦炎能明显改善患者的临床症状,提高患者的鼻黏膜纤毛传输功能。Objective To explore the effect of chymotrypsin for injection combined with nasal negative pressure replacement in the treatment of chronic sinusitis.Methods 60 patients with chronic sinusitis were randomly divided into two groups.The control group was treated with nasal negative pressure replacement,and the study group was treated with chymotrypsin for injection combined with nasal negative pressure replacement.The treatment effects of the two groups were compared.Results After treatment,the total effective rate,MCC and MTR in the study group were higher than those in the control group,and the Lund-Kennedy score and Lund-Mackey score were lower than those in the control group(P<0.05).Conclusions Chymotrypsin for injection combined with nasal negative pressure replacement in the treatment of chronic sinusitis can obviously improve the clinical symptoms and improve the nasal mucociliary transport function of patients.

关 键 词：注射用糜蛋白酶 鼻负压置换 慢性鼻窦炎 疗效 

分 类 号：R765.41[医药卫生—耳鼻咽喉科]