2012—2023年大理州90例片形吸虫病病例实验室检测资料回顾性分析  

Retrospective analysis of laboratory test data of 90 cases of fascioliasis in Dali Prefecture from 2012 to 2023

作　　者：杨丽群 陈凤 李芹翠 段晓云 李荣 高媛媛 YANG Liqun;CHEN Feng;LI Qincui;DUAN Xiaoyun;LI Rong;GAO Yuanyuan(Institute of Schistosomiasis Prevention and Control,Dali Bai Autonomous Prefecture,Dali 671000,Yunnan Province,China)

机构地区：[1]大理白族自治州血吸虫病防治研究所,云南大理671000

出　　处：《寄生虫病与感染性疾病》2024年第4期198-202,共5页Parasitoses and Infectious Diseases

基　　金：国家寄生虫资源库资助项目(项目编号:NPRC-2019-194-30)。

摘　　要：目的 回顾分析片形吸虫病病例实验室检测指标变化特点,为早期准确诊断片形吸虫病提供合理指导。方法 收集2012—2023年大理州90例片形吸虫病病例(31例确诊病例、59例临床诊断病例)药物治疗前实验室检测资料,回顾分析其血常规参数、血清特异性抗体、大便虫卵检测等相关结果。采用SPSS 20.0软件分析数据,数值范围用均值(极小值~极大值)表示。数据比较采用t检验、χ^(2)检验和Fisher确切概率法。以P<0.05为差异有统计学意义。结果 90例片形吸虫病病例血常规以嗜酸性粒细胞百分比显著增高为特点,增高比例100.0%,增幅均值达30.3%,同时伴11.1%病例Hb降低、36.7%病例血小板增高;血清片形吸虫特异性抗体阳性率100.0%,同步检测其他寄生虫抗体,存在不同比例阳性反应;大便虫卵阳性检出率为34.4%,CT/MRI或彩超检查均提示肝胆病变。结论 片形吸虫病相关实验室检测指标呈现不同变化特点及应用价值,综合分析与评估检测结果有利于提高片形吸虫病早期诊断效率。Objective To retrospectively analyze the changing characteristics of laboratory test indexes in patients with fascioliasis infection, and to provide reasonable guidance for early and accurate diagnosis of fascioliasis infection. Methods The laboratory test data of 90 cases of fascioliasis(31confirmed cases and 59 clinically diagnosed cases) before drug treatment in Dali Prefecture from2012 to 2023 were collected, and the blood routine parameters, serum specific antibodies, stool egg detection and other relevant results were retrospectively analyzed. SPSS 20.0 software was used to analyze the data, and the value range was represented by the mean value(minimum value to maximum value). Data were compared by t test, Chi-square test and Fisher exact probability method. P<0.05 indicated that the difference was statistically significant. Results The blood routine of 90 cases of fascioliasis was characterized by a significant increase in eosinophilic granulocyte percentage(100.0%), with an average increase of 30.3%, accompanied by Hb decrease in 11.1%cases and platelet increase in 36.7% cases. The positive rate of serum antibodies against fluke fasciola was 100.0%. The antibodies against other parasites were detected simultaneously,and there were positive reactions in different proportions. The positive detection rate of stool eggs was34.4%, and CT/MRI(computed tomography/magnetic resonance imaging) or color ultrasound showed hepatobiliary disease. Conclusions There were different changing characteristics and application value of laboratory detection indicators of fascioliasis. Comprehensive analysis and evaluation of the detection results are conducive to improving the efficiency of early diagnosis of fascioliasis.

关 键 词：片形吸虫病 实验室检测 感染 诊断 

分 类 号：R532.2[医药卫生—内科学]