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作 者:罗菊奉 岳冀蓉[1,2] Luo Jufeng;Yue Jirong(Center of Gerontology and Geriatrics,West China Hospital,Sichuan University,Chengdu 610041,Sichuan,China;National Clinical Research Center for Geriatrics,West China Hospital,Sichuan University,Chengdu 610041,Sichuan,China)
机构地区:[1]四川大学华西医院老年医学研究中心,成都610041 [2]四川大学华西医院、国家老年疾病临床医学研究中心,成都610041
出 处:《中华老年医学杂志》2024年第12期1538-1544,共7页Chinese Journal of Geriatrics
基 金:四川省中央引导地方科技发展专项-科技创新基地建设(2023ZYD0173)。
摘 要:肌脂比是评估肌肉与脂肪平衡的关键指标,可通过生物电阻抗、双能X线吸收法等方法测定。相较于仅依赖体质指数或腰围的传统肥胖诊断,肌脂比能提供更为全面的机体状态信息,且它与多种健康风险紧密关联,特别是代谢疾病与心血管疾病,而肌少性肥胖旨在捕捉心血管代谢性疾病和功能衰退的风险,因此肌脂比特别适用于早期识别或诊断肌少性肥胖症患者。肌脂比还与多种疾病预后和不良临床结局的发生风险相关,因此它的应用不仅限于疾病的筛查和诊断,还可以作为指导干预措施的重要依据。肌脂比具有广阔的应用前景,将在改善全球人口健康、延缓衰老进程和防治相关疾病中发挥日益重要的作用。The muscle-fat ratio is a crucial indicator for assessing the balance between muscle and fat,which can be evaluated using methods such as bioelectrical impedance and dual-energy X-ray absorptiometry.In contrast to traditional obesity diagnoses that rely solely on body mass index or waist circumference,the muscle-fat ratio offers a more comprehensive overview of the body's condition.It is closely linked to various health risks,particularly metabolic and cardiovascular diseases.Sarcopenic obesity seeks to capture the risks associated with cardiometabolic diseases and functional decline,making the muscle-fat ratio particularly suitable for the early identification and diagnosis of patients with this condition.Furthermore,the muscle-fat ratio correlates with the prognosis of various diseases and the risk of adverse clinical outcomes.Consequently,its application extends beyond disease screening and diagnosis,serving as a vital foundation for guiding intervention measures.Given its broad application prospects,the muscle-fat ratio is poised to play an increasingly significant role in enhancing global population health,delaying the aging process,and preventing and treating related diseases.
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