从风痰瘀虚论治儿童咳嗽变异性哮喘的理论探索及临床运用  

The theoretical exploration and clinical application of treating cough variant asthma in children from the aspects of wind,phlegm,stasis and deficiency

作　　者：符新蕾 黄夏婷 罗巧梅 吴欣丽 陈四文[2] FU Xinlei

机构地区：[1]福建中医药大学,福建福州350108 [2]福建中医药大学附属厦门中医院,福建厦门361000

出　　处：《中医临床研究》2024年第32期87-91,共5页Clinical Journal Of Chinese Medicine

基　　金：福建省自然科学基金项目(2023J0112);第五批全国中医临床优秀人才研修项目(国中医药人教函[2022]1号)。

摘　　要：咳嗽变异性哮喘作为一种特殊类型的哮喘,以慢性咳嗽为主要临床表现,较少伴随喘息、气促、呼吸困难等典型的哮喘症状,是常见的儿童肺系疾病之一。该病反复发作,时作时止,迁延难愈。近年来,儿童咳嗽变异性哮喘的发病率逐年增高,需要引起重视。中医更加注重既病防变、已病防复,在治疗咳嗽变异性哮喘方面具有独特优势。临床研究表明,中医治疗咳嗽变异性哮喘可以有效改善肺功能、降低复发率、缓解临床症状,已经成为越来越多患儿及家长的选择。咳嗽变异性哮喘属于中医“哮咳、顽咳、风咳”的范畴,随着后世医家对该病的阐释和发挥,相关理论也在不断地丰富与发展。基于各家学说和中医古籍,结合中医治疗咳嗽变异性哮喘患儿用药规律的数据挖掘结果,可知该病的基本病机为本虚标实,本虚以肺、脾、肾不足为主,标实为风、痰、瘀内存,风、痰、瘀、虚四者与咳嗽变异性哮喘的关系密切。本研究以此为切入点,探讨各医家从风、痰、瘀、虚四个方面论治咳嗽变异性哮喘的理论及学术经验,同时与现代医学相结合,发现消风、祛痰、化瘀、补虚法治疗咳嗽变异性哮喘与现代医学中抑制炎症反应、降低气道高反应性、调节免疫功能、缓解气管痉挛、延缓气道重塑等理念不谋而合,为中医治疗咳嗽变异性哮喘提供理论依据,总结现代医家从风、痰、瘀、虚治疗该病的临床经验,以期为儿童咳嗽变异性哮喘的临床治疗提供思路。Cough variant asthma(CVA),as a special type of asthma with chronic cough as the main clinical manifestation,is Cless often accompanied by wheezing,shortness of breath,dyspnea and other typical asthma symptoms,and is one of the common pulmonary diseases in children.The disease is recurrent,intermittent,and difficult to be cured.In recent years,the incidence of CVA in children has been increasing year by year,which needs to attract the attention of parents and health departments.Traditional Chinese medicine(TCM)pays more attention to preventing changes or recurrence of existing diseases,and has unique advantages in the treatment of CVA.According to clinical research,treating CVA in TCM can effectively improve lung function,reduce the recurrence rate,and alleviate clinical symptoms,which has become the choice of more and more children and parents.CVA belongs to the category of asthmatic cough,persistent cough and wind cough in TCM,and its related theories have been enriched and developed with the interpretation and play of the disease by medical doctors of later generations.Based on various theories and ancient TCM books,combined with the data mining results of the medication rule of Chinese medicine on CVA in children,it can be seen that the basic pathogenesis of the disease is deficiency in origin and excess in superficiality.The deficiency of lung,spleen and kidney is the main cause of deficiency in origin,while the excess in superficiality is the internal presence of wind,phlegm,and blood stasis.Wind,phlegm,blood stasis,and deficiency are closely related to CVA.This paper explores the theories and academic experiences of various medical practitioners in treating CVA from the four aspects of wind,phlegm,blood stasis,and deficiency,and at the same time combines them with modern medicine,finding that treating CVA by the methods of dispelling wind,exempting phlegm,resolving blood stasis,and tonifying coincides with the concepts of suppressing inflammation,reducing bronchial hyperresponsiveness,regulating immune func

关 键 词：风 痰 瘀 虚 儿童咳嗽变异性哮喘 

分 类 号：R256.12[医药卫生—中医内科学]