三痹汤联合颈周针刺治疗风寒湿型神经根型颈椎病临床研究  

Clinical Study on Sanbi Decoction Combined with Cervical Acupuncture for Cervical Spondylotic Radiculopathy of Wind-Cold-Damp Type

作　　者：宋琪 金昕[2] 昌辉 SONG Qi;JIN Xin;CHANG Hui(Department of Chinese Massage,Chun'an County Traditional Chinese Medicine Hospital,Chun'an Zhejiang 311700,China;Department of Chinese Massage,Zhejiang Provincial Hospital of Chinese Medicine,Hangzhou Zhejiang 310003,China)

机构地区：[1]淳安县中医院推拿科,浙江淳安311700 [2]浙江省中医院推拿科,浙江杭州310003

出　　处：《新中医》2024年第13期53-57,共5页New Chinese Medicine

摘　　要：目的:观察三痹汤联合颈周针刺治疗风寒湿型神经根型颈椎病(CSR)的临床疗效。方法:选取CSR患者102例,按随机数字表法分为西药组和联合组各51例。2组均予颈牵引康复,西药组采用塞来昔布胶囊治疗,联合组在西药组基础上予三痹汤联合颈周针刺治疗。2组连续治疗4周。评价2组临床疗效,比较2组症状体征与风寒湿证评分,检测血清前列腺素E_(2)(PGE_(2))、P物质(SP)、五羟色胺(5-HT)水平。结果:联合组总有效率为92.16%,高于西药组74.51%(P<0.05)。治疗2周、4周后,2组颈椎病临床评价量表(CASCS)评分较治疗前增加(P<0.05),且联合组CASCS评分高于同时间点西药组(P<0.05)。治疗2周、4周后,2组风寒湿证评分较治疗前降低(P<0.05),且联合组风寒湿证评分低于同时间点西药组(P<0.05)。治疗后,2组血清PGE_(2)、SP、5-HT水平较治疗前降低(P<0.05),且联合组血清PGE_(2)、SP、5-HT水平低于西药组(P<0.05)。结论:三痹汤联合颈周针刺治疗风寒湿型CSR的临床疗效显著,能促进患者症状与中医证候的好转,下调疼痛介质水平。Objective:To observe the clinical effect of the therapy of Sanbi Decoction combined with cervical acupuncture on cervical spondylotic radiculopathy(CSR)of wind-cold-damp type.Methods:A total of 102 CSR patients were selected and divided into the western medicine group and the combination group according to the random number table method,with 51 cases in each group.The two groups were given neck traction for rehabilitation;the western medicine group was treated with Celecoxib Capsules,and the combination group was given Sanbi Decoction combined with cervical acupuncture based on the treatment of the western medicine group.The two groups were treated for four weeks.The clinical effects in the two groups were evaluated,and the symptoms and signs as well as scores of wind-cold-damp syndrome were compared between the two groups.The levels of serum prostaglandin E_(2)(PGE_(2)),substance P(SP)and 5-hydroxytryptamine(5-HT)were detected.Results:The total effective rate was 92.16%in the combination group,higher than that of 74.51%in the western medicine group(P<0.05).After two weeks and four weeks of treatment,the scores of the Clinical Assessment Scale for Cervical Spondylosis(CASCS)in the two groups were increased when compared with those before treatment(P<0.05),and the CASCS score in the combination group was higher than that in the western medicine group at the same time point(P<0.05).After 2 weeks and 4 weeks of treatment,the scores of wind-cold-damp syndrome in the two groups were decreased when compared with those before treatment(P<0.05),and the score of windcold-damp syndrome in the combination group was lower than that in the western medicine group at the same time point(P<0.05).After treatment,the levels of serum PGE_(2),SP and 5-HT in the two groups were decreased when compared with those before treatment(P<0.05),and the levels of serum PGE_(2),SP and 5-HT in the combination group were lower than those in the western medicine group(P<0.05).Conclusion:The therapy of Sanbi Decoction combined with cervical acupun

关 键 词：神经根型颈椎病 风寒湿型 三痹汤 针刺 前列腺素E2 P物质 五羟色胺 

分 类 号：R681.55[医药卫生—骨科学]