应用激光散斑成像技术观察守神对针刺健康受试者合谷穴局部微循环的影响  

The Effect of Mentality-Controlling on Local Microcirculation of Acupuncture at Hegu(LI 4)by Application of Laser Speckle Contrast Imaging

作　　者：陈月彩 向蒙 池响峰[2] 李根新 陈钧杰 余瑾[1] CHEN Yuecai;XIANG Meng;CHI Xiangfeng;LI Genxin;CHEN Junjie;YU jin(Guangzhou University of Chinese Medicine,Guangzhou,510006;Guangdong Second Traditional Chinese Medicine Hospital)

机构地区：[1]广州中医药大学,广东省广州市510006 [2]广东省第二中医院

出　　处：《中医杂志》2024年第23期2457-2460,共4页Journal of Traditional Chinese Medicine

基　　金：广东省传感技术与生物医疗仪器重点实验室项目(2020B1212060077)。

摘　　要：目的观察在针刺时进行守神对合谷穴局部微循环的影响。方法将40例健康受试者随机分为单纯针刺组和针刺守神组各20例。单纯针刺组在受试者右手合谷穴上针刺。针刺守神组在进行针刺手法捻转后留针5 min时播放一段音频引导受试者针刺守神。用激光散斑血流成像仪采集两组受试者针刺前静息态(R1)、进针(A1)、转针(A2)及拔针后(R2)4个阶段各5 min的微循环血流灌注量(MBPU)并进行比较,同时比较两组受试者针刺时的主观感受如放松、精神集中、有睡意、穴位有能量流动情况,并记录不良反应。结果针刺守神组R1、A1、A2、R2阶段MBPU分别为(67.92±18.40)PU、(168.13±46.03)PU、(144.19±44.40)PU、(159.73±65.21)PU,单纯针刺组分别为79.85(66.80,99.40)PU、193.31(173.15,224.80)PU、147.68(128.12,198.30)PU、158.09(126.05,207.59)PU。两组4个阶段的MBPU整体比较差异有统计学意义(P<0.01);其中两组A1阶段MBPU大于R1阶段,A2阶段MBPU小于A1阶段,R2阶段MBPU大于R1(P<0.01);针刺守神组R2阶段MBPU大于A2阶段(P<0.05)。针刺守神组A2与A1的MBPU差值小于单纯针刺组,差异具有统计学意义(t=3.79,P<0.01)。针刺守神组受试者感到放松有18例(90%),精神集中有15例(75%),有睡意3例(15%),穴位感到有能量流动14例(70%);单纯针刺组受试者感到放松、有睡意各13例(65%),精神集中、感到穴位有能量流动各6例(30%)。针刺守神组精神集中、穴位感到有能量流动人数多于单纯针刺组,有睡意人数少于单纯针刺组(P<0.05)。两组受试者均未出现晕针、针刺部位感染、局部血肿等不良反应。结论针刺可以影响局部微循环的变化,患者在针刺时进行守神可以减缓MBPU的降低速度并增强针刺后效应,且安全性良好。Objective To explore the effect of mentality-controlling on local microcirculation of acupuncture at Hegu(LI 4).Methods Forty healthy subjects were randomly divided into simple acupuncture group and mentalitycontrolling acupuncture group,with 20 cases in each group.The simple acupuncture group was acupunctured at Hegu(LI 4)on the right hand of the patient.In mentality-controlling acupuncture group,an audio clip was played to guide the participants to control their mentality when needle retention for 5 min after performing acupuncture twirling manipulation.The microcirculatory blood perfusion units(MBPU)was captured and compared between groups of partici⁃pants using laser speckle contrast imaging(LSCI)for 5 mins in each of the four stages,state before acupuncture(R1),after needle insertion(A1),after needle twirling(A2)and after needle withdrawal(R2).The participants'feelings such as relaxation,concentration,drowsiness,energy flow at acupoints were compared between groups,and the adverse reactions were recorded.Results The MBPU values of R1,A1,A2 and R2 stages in mentality-controlling acupuncture group were 67.92±18.40 PU,168.13±46.03 PU,144.19±44.40 PU,159.73±65.21 PU,respectively.The simple acupuncture group were 79.85(66.80,99.40)PU,193.31(173.15,224.80)PU,147.68(128.12,198.30)PU,158.09(126.05,207.59)PU respectively.There was a statistically significant difference in MBPU between groups of the four stages(P<0.01).Among them,the MBPU in the A1 stage of both groups was significantly larger than that in the R1 stage,the MBPU in the A2 stage significantly smaller than that in the A1 stage,and the MBPU in the R2 stage was significantly larger than that in the R1 stage(P<0.01).MBPU in the R2 stage of the mentality-controlling acupuncture group was larger than that in the A2 stage(P<0.05).The difference of MBPU between A2 and A1 in mentality-controlling acupuncture group was significantly smaller than that in the simple acu⁃puncture group,and the difference was statistically significant(t=3.79,P<0.01).In mental

关 键 词：针刺 守神 合谷穴 微循环血流灌注量 激光散斑成像技术 

分 类 号：R246[医药卫生—针灸推拿学]