A cucurbit[8]uril-based supramolecular phosphorescent assembly:Cell imaging and sensing of amino acids in aqueous solution  

作　　者：Qian Ren Xue Dai Ran Cen Yang Luo Mingyang Li Ziyun Zhang Qinghong Bai Zhu Tao Xin Xiao 

机构地区：[1]Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province,Institute of Applied Chemistry,Guizhou University,Guiyang 550025,China

出　　处：《Chinese Chemical Letters》2024年第12期165-168,共4页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(No.22361011);Guizhou Provincial Science and Technology Projects(No.ZK[2023]General 040)。

摘　　要：In recent years,host-guest interactions of macrocycles have emerged as a promising approach to effectively enhance pure organic room-temperature phosphorescence by inhibiting the nonradiative relaxation while isolating the effects of oxygen and water molecules.In this work,a supramolecular assembly Q[8]-BCPI was constructed by 6-bromoisoquinoline derivative(BCPI)and cucurbit[8]uril(Q[8]).The assembly produced intense green room temperature phosphorescence(RTP)emission and enabled supramolecular recognition and detection of L-tryptophan(L-Trp)and L-tyrosine(L-Tyr).Moreover,the Q[8]-BCPI assembly showed good biocompatibility and low biotoxicity,and had a good staining effect on HeLa cells.

关 键 词：CUCURBITURIL Isobromoquinoline Pure organic room-temperature PHOSPHORESCENT Cell imaging Amino acid 

分 类 号：O641.3[理学—物理化学]