Chemoselective photocatalytic sulfenylamination of alkenes with sulfenamides via energy transfer  

作　　者：Er-Meng Wang Ziyi Wang Xu Ban Xiaowei Zhao Yanli Yin Zhiyong Jiang 

机构地区：[1]Henan Key Laboratory of Natural Medicine Innovation and Transformation,Henan University,Kaifeng 475004,China [2]School of Chemistry and Chemical Engineering,Henan Normal University,Xinxiang 453007,China [3]College of Advanced Interdisciplinary Science and Technology,Henan University of Technology,Zhengzhou 450001,China

出　　处：《Chinese Chemical Letters》2024年第12期433-439,共7页中国化学快报（英文版）

基　　金：financial support from the National Natural Science Foundation of China(Nos.22171072,21925103,and22301061)。

摘　　要：β-Amino sulfides hold significant biological importance,motivating the development of several methods for sulfenylamination of alkenes.However,these methods often involve a three-component system with limited alkene substrate range.In this study,we present a pioneering two-component approach utilizing readily accessible sulfenamides as efficient difunctionalization reagents.Key to its success is the careful selection of a suitable photosensitizer,which enables precise modulation of sulfenamides by promoting unprecedented energy transfer rather than traditional single-electron oxidation.This novel strategy leads to the concurrent formation of N-and S-radical species,ensuring high regioselectivity for both electronneutral and electron-deficient alkenes.As a result,a wide range of valuableβ-amino sulfides,including those with congested amine groups,can be readily synthesized.These findings highlight the potential of this method for the efficient synthesis of diverse functionalizedβ-amino sulfides.

关 键 词：PHOTOCATALYSIS Energy transfer Sulfenamides Sulfenylamination ALKENES 

分 类 号：O621.251[理学—有机化学]